购物车
全部删除
  • TargetMol
    您的购物车当前为空
前往下单页继续购物
顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-MRE11 Antibody (6E413)

一键复制产品信息
Rating icon 还可以
货号 TMAB-08988

Anti-MRE11 Antibody (6E413) 是一种 Rabbit 抗体，靶向 MRE11。Anti-MRE11 Antibody (6E413) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-MRE11 Antibody (6E413)

Anti-MRE11 Antibody (6E413)

一键复制产品信息
Rating icon 还可以
货号 TMAB-08988

Anti-MRE11 Antibody (6E413) 是一种 Rabbit 抗体，靶向 MRE11。Anti-MRE11 Antibody (6E413) 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,485
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
大包装 & 定制
加入购物车
TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
资源下载:
产品操作手册

产品介绍

生物活性
产品描述
Anti-MRE11 Antibody (6E413) is a Rabbit antibody targeting MRE11. Anti-MRE11 Antibody (6E413) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
6E413
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-1000; IHC-P: 1:50-200; IHC-Fr: 1:400-800; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus. Note=Localizes to discrete nuclear foci after treatment with genotoxic agents.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
Recombinant Protein: human MRE11
抗原种属
Human
基因名称
MRE11
基因ID
4361
蛋白名称
Double-strand break repair protein MRE11
Uniprot ID
P49959
功能
Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. This could facilitate searches for short or long regions of sequence homology in the recombining DNA templates, and may also stimulate the activity of DNA ligases and/or restrict the nuclease activity of MRE11A to prevent nucleolytic degradation past a given point. The complex may also be required for DNA damage signaling via activation of the ATM kinase. In telomeres the MRN complex may modulate t-loop formation.
化学信息
分子量Theoretical: 80 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
Related Tags: buy Anti-MRE11 Antibody (6E413) | purchase Anti-MRE11 Antibody (6E413) | Anti-MRE11 Antibody (6E413) cost | order Anti-MRE11 Antibody (6E413) | Anti-MRE11 Antibody (6E413) molecular weight