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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-ENPP4 Polyclonal Antibody

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货号 TMAB-05588

Anti-ENPP4 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ENPP4。Anti-ENPP4 Polyclonal Antibody 可用于 WB。

Anti-ENPP4 Polyclonal Antibody

Anti-ENPP4 Polyclonal Antibody

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货号 TMAB-05588

Anti-ENPP4 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ENPP4。Anti-ENPP4 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-ENPP4 Polyclonal Antibody is a Rabbit antibody targeting ENPP4. Anti-ENPP4 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Single-pass type I membrane protein.
组织特异性Expressed on the surface of vascular endothelia.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景ENPP4 is a 453 amino acid single-pass type I membrane protein that belongs to the nucleotide pyrophosphatase/phosphodiesterase family. The gene that encodes NPP4 consists of approximately 16,736 bases and maps to human chromosome 6p21.1. Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene, and Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins are also located on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6.
抗原信息
免疫原
KLH conjugated synthetic peptide: human ENPP4
抗原种属
Human
基因名称
ENPP4
基因ID
22875
蛋白名称
Bis(5'-adenosyl)-triphosphatase ENPP4
Uniprot ID
Q9Y6X5
功能
Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors.
化学信息
分子量Theoretical: 52 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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