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Anti-NFAT1 Antibody (4I426)

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产品编号 TMAC-02795
别名 T-cell transcription factor NFAT1, T cell transcription factor NFAT 1, Preexisting nuclear factor of activated T cells 2, preexisting component, Nuclear factor of activated T-cells, Nuclear factor of activated T cells pre-existing component, Nuclear factor of activated T cells cytoplasmic calcineurin dependent 2, Nuclear factor of activated T cells cytoplasmic 2, Nuclear factor of activated T cells, NF-ATp, NFATp, NF-ATc2, NFATc2, NFAT1-D, NFAT1, NFAT transcription complex, NFAT pre-existing subunit, NFAT pre existing subunit, NFAT 1, NFAC2_HUMAN, NF ATp, NF ATc2, KIAA0611, cytoplasmic 2, AI607462

Anti-NFAT1 Antibody (4I426) 是一种 Rabbit 抗体，靶向 NFAT1。Anti-NFAT1 Antibody (4I426) 可用于 FCM,ICC/IF,IHC,WB。

Anti-NFAT1 Antibody (4I426)

Anti-NFAT1 Antibody (4I426)

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产品编号 TMAC-02795 别名 T-cell transcription factor NFAT1, T cell transcription factor NFAT 1, Preexisting nuclear factor of activated T cells 2, preexisting component, Nuclear factor of activated T-cells, Nuclear factor of activated T cells pre-existing component, Nuclear factor of activated T cells cytoplasmic calcineurin dependent 2, Nuclear factor of activated T cells cytoplasmic 2, Nuclear factor of activated T cells, NF-ATp, NFATp, NF-ATc2, NFATc2, NFAT1-D, NFAT1, NFAT transcription complex, NFAT pre-existing subunit, NFAT pre existing subunit, NFAT 1, NFAC2_HUMAN, NF ATp, NF ATc2, KIAA0611, cytoplasmic 2, AI607462

Anti-NFAT1 Antibody (4I426) 是一种 Rabbit 抗体，靶向 NFAT1。Anti-NFAT1 Antibody (4I426) 可用于 FCM,ICC/IF,IHC,WB。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-NFAT1 Antibody (4I426) is a Rabbit antibody targeting NFAT1. Anti-NFAT1 Antibody (4I426) can be used in FCM,ICC/IF,IHC,WB.
别名T-cell transcription factor NFAT1, T cell transcription factor NFAT 1, Preexisting nuclear factor of activated T cells 2, preexisting component, Nuclear factor of activated T-cells, Nuclear factor of activated T cells pre-existing component, Nuclear factor of activated T cells cytoplasmic calcineurin dependent 2, Nuclear factor of activated T cells cytoplasmic 2, Nuclear factor of activated T cells, NF-ATp, NFATp, NF-ATc2, NFATc2, NFAT1-D, NFAT1, NFAT transcription complex, NFAT pre-existing subunit, NFAT pre existing subunit, NFAT 1, NFAC2_HUMAN, NF ATp, NF ATc2, KIAA0611, cytoplasmic 2, AI607462
Ig Type
IgG
克隆号
4I426
交叉反应
Human
验证活性
1. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-NFAT1 antibody. Counter stained with hematoxylin.
2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-NFAT1 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-NFAT1 antibody. Counter stained with hematoxylin.
4. ICC staining NFAT1 in MCF-7 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
5. ICC staining NFAT1 in Hela cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
6. ICC staining NFAT1 in SHG-44 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
7. Flow cytometric analysis of Jurkat cells with NFAT1 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
verifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivity
应用FCMICC/IFIHCWB
推荐剂量
WB: 1:500; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The NFAT (nuclear factor of activated T cells) family of transcription factors regulates cytokine expression in T cells. Members of the family include NFATc1 (NFATc), NFATc2 (NFATp), NFATn, NFATc3 (NFAT4, NFATx) and NFATc4 (NFAT3). Recognition of antigen by the T cell receptor (TCR) eventually activates the calcium-dependent protein phosphatase calcineurin. Once activated, calcineurin stimulates the translocation of NFATc1 (cytoplasmic) from the cytoplasm to the nucleus where it associates with NFATn (nuclear). Like NFATc1, NFATc2 resides in the cytoplasm and translocates to the nucleus subsequent to activation of calcineurin. Once in the nucleus, NFATc2 synergizes with AP-1 transcription factors to initiate transcription of cytokine genes. NFATc3 and NFATc4 share 65% sequence identity with other members of the NFAT family. They are similar to NFATc2 in that they also synergize with the AP-1 family of proteins.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
Q13469
化学信息
分子量Theoretical: 135 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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