规格

价格

库存

数量

2 mg

¥ 399

现货

生物活性

产品描述	N-deacetylated BMS-202 is an inhibitor of PD-1/PD-L1 interactions and has potential anticancer activity for cancer research.
体外活性	N-deacetylated BMS-202 inhibits PD-1/PD-Ll interaction, and may augment therapeutic immune response to a number of histologically distinct tumors. Blockade of the PD-1/PD-Ll ligation using antibodies to PD-Ll has been shown to restore and augment T cell activation in many systems[1].

化学信息

分子量	377.48
分子式	C₂₃H₂₇N₃O₂
CAS No.	2310135-18-1
Smiles	N=1C(OCC2=CC=CC(C=3C=CC=CC3)=C2C)=CC=C(C1OC)CNCCN
密度	1.127 g/cm3 (Predicted)
颜色	Yellow
物理性状	Solid

储存&溶解度

存储

store at low temperature | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 30 mg/mL (79.47 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (5.3 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO