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Anti-GART Antibody (9K216)

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Anti-GART Antibody (9K216)
产品编号 TMAC-01625
别名 Trifunctional purine biosynthetic protein adenosine 3, PUR2_HUMAN, PRGS, Phosphoribosylglycinamide synthetase, Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase, Phosphoribosylglycinamide formyltransferase, EC 2.1.2.29, Phosphoribosylglycinamide formyltransferase phosphoribosylglycinamide synthetase phosphoribosylaminoimidazole synthetase, Phosphoribosylglycinamide formyltransferase, Phosphoribosyl-aminoimidazole synthetase, PGFT, PAIS, MGC47764, Glycinamide ribonucleotide synthetase, GARTF, GART, GARS, GAR transformylase, AIRS, AIR synthase, 5'-phosphoribosylglycinamide transformylase

Anti-GART Antibody (9K216) 是一种 Rabbit 抗体,靶向 GART。Anti-GART Antibody (9K216) 可用于 WB,ICC/IF,IHC,IP。

Anti-GART Antibody (9K216)

Anti-GART Antibody (9K216)

Rating icon 还可以
Anti-GART Antibody (9K216)
产品编号 TMAC-01625 别名 Trifunctional purine biosynthetic protein adenosine 3, PUR2_HUMAN, PRGS, Phosphoribosylglycinamide synthetase, Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase, Phosphoribosylglycinamide formyltransferase, EC 2.1.2.29, Phosphoribosylglycinamide formyltransferase phosphoribosylglycinamide synthetase phosphoribosylaminoimidazole synthetase, Phosphoribosylglycinamide formyltransferase, Phosphoribosyl-aminoimidazole synthetase, PGFT, PAIS, MGC47764, Glycinamide ribonucleotide synthetase, GARTF, GART, GARS, GAR transformylase, AIRS, AIR synthase, 5'-phosphoribosylglycinamide transformylase

Anti-GART Antibody (9K216) 是一种 Rabbit 抗体,靶向 GART。Anti-GART Antibody (9K216) 可用于 WB,ICC/IF,IHC,IP。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-GART Antibody (9K216) is a Rabbit antibody targeting GART. Anti-GART Antibody (9K216) can be used in WB,ICC/IF,IHC,IP.
别名Trifunctional purine biosynthetic protein adenosine 3, PUR2_HUMAN, PRGS, Phosphoribosylglycinamide synthetase, Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase, Phosphoribosylglycinamide formyltransferase, EC 2.1.2.29, Phosphoribosylglycinamide formyltransferase phosphoribosylglycinamide synthetase phosphoribosylaminoimidazole synthetase, Phosphoribosylglycinamide formyltransferase, Phosphoribosyl-aminoimidazole synthetase, PGFT, PAIS, MGC47764, Glycinamide ribonucleotide synthetase, GARTF, GART, GARS, GAR transformylase, AIRS, AIR synthase, 5'-phosphoribosylglycinamide transformylase
Ig Type
IgG
克隆号
9K216
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of GART on different lysates using anti-GART antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: 293T, Lane 3: A431.
2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-GART antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded mouse uterus tissue using anti-GART antibody. Counter stained with hematoxylin.
4. ICC staining GART in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
5. ICC staining GART in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
6. ICC staining GART in SW480 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
推荐剂量
WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Purines are critical for energy metabolism, cell signaling and cell reproduction and also function as precursors for coenzymes, energy transfer molecules, regulatory factors and proteins involved in RNA and DNA synthesis. GART (GAR transformylase), also referred to as AIRS, GARS, PAIS, PGFT, PRGS or GARTF, is 1,010 amino acids in length and is a key folate-dependent trifunctional enzyme with phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase and AICAR (phosphoribosylaminoimidazole synthetase) activity required for de novo purine biosynthesis. Cancer cells require considerable amounts of purines to sustain their accelerated growth and GART is, therefore, a target for cancer chemotherapy. GART is highly conserved in vertebrates. Two isoforms of GART are expressed due to alternative splicing events.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 107 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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