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Anti-Junctional Adhesion Molecule 1 Antibody (7I445)

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Anti-Junctional Adhesion Molecule 1 Antibody (7I445)
产品编号 TMAC-02292
别名 Platelet F11 receptor, Platelet adhesion molecule 1, Junctional adhesion molecule A, Junctional adhesion molecule 1

Anti-Junctional Adhesion Molecule 1 Antibody (7I445) 是一种 Rabbit 抗体，靶向 Junctional Adhesion Molecule 1。Anti-Junctional Adhesion Molecule 1 Antibody (7I445) 可用于 WB,IHC。

Anti-Junctional Adhesion Molecule 1 Antibody (7I445)

Anti-Junctional Adhesion Molecule 1 Antibody (7I445)

Rating icon 还可以
Anti-Junctional Adhesion Molecule 1 Antibody (7I445)
产品编号 TMAC-02292 别名 Platelet F11 receptor, Platelet adhesion molecule 1, Junctional adhesion molecule A, Junctional adhesion molecule 1

Anti-Junctional Adhesion Molecule 1 Antibody (7I445) 是一种 Rabbit 抗体，靶向 Junctional Adhesion Molecule 1。Anti-Junctional Adhesion Molecule 1 Antibody (7I445) 可用于 WB,IHC。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-Junctional Adhesion Molecule 1 Antibody (7I445) is a Rabbit antibody targeting Junctional Adhesion Molecule 1. Anti-Junctional Adhesion Molecule 1 Antibody (7I445) can be used in WB,IHC.
别名Platelet F11 receptor, Platelet adhesion molecule 1, Junctional adhesion molecule A, Junctional adhesion molecule 1
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of JAM-1 on different lysates using anti-JAM-1 antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: Human liver.
2. Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-JAM-1 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-JAM-1 antibody. Counter stained with hematoxylin.
应用
WB
IHC
推荐剂量
WB: 1:1000-5000; IHC: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Junctional adhesion molecule (JAM) is a member of the immunoglobulin superfamily expressed in tight junctions of epithelial cells and endothelial cells. It is implicated in transendothelial migration of leukocytes. JAM is constitutively expressed on circulating monocytes, neutrophils, lymphocyte subsets and platelets. The JAM family consists of JAM-A, JAM-B and JAM-C, alternatively designated JAM-1, JAM-2 and JAM-3, respectively. JAM-A localizes with F-Actin at the cell-cell contacts and at the membrane ruffles. It is involved in cell to cell adhesion through homophilic interactions and plays a role in the organization of tight junctions and modulation of leukocyte extravasation. JAM-B interacts with discrete subsets of PBLs, suggesting that it may play a role in lymphocyte trafficking. JAM-B and JAM-C proteins are binding partners; JAM-C may be a functional JAM-B receptor. Specifically, JAM-B adheres to T cells through heterotypic interactions with JAM-C. The JAM-B/JAM-C interaction my play a role in T, NK and dendritic cellular inflammation.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
Q9Y624
化学信息
分子量Theoretical: 33 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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