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Anti-ZNF649 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ZNF649。Anti-ZNF649 Polyclonal Antibody 可用于 WB。
Anti-ZNF649 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ZNF649。Anti-ZNF649 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
| 产品描述 | Anti-ZNF649 Polyclonal Antibody is a Rabbit antibody targeting ZNF649. Anti-ZNF649 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Human |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Highly expressed in heart, skeletal muscle, and brain. Lower expression in liver, lung, kidney, pancreas and placenta. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger protein 649 (ZNF649) is a 505 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZNF649 is highly expressed in heart, brain and skeletal muscle with lower levels of expression in lung, liver, kidney and pancreas. ZNF649 contains ten C2H2-type zinc fingers and one KRAB domain through which it is thought to be involved in DNA-binding and transcriptional repression of mitogen-activated protein kinase signaling pathways. |
| 免疫原 | KLH conjugated synthetic peptide: human ZNF649 |
| 抗原种属 | Human |
| 基因名称 | ZNF649 |
| 基因ID | |
| 蛋白名称 | Zinc finger protein 649 |
| Uniprot ID | |
| 功能 | Transcriptional repressor. Regulator of transcriptional factor complexes and may suppress SRE and AP-1 transcription activities mediated by growth factor signaling pathways. |
| 分子量 | Theoretical: 58 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |