Poloxamer 122 L42 is a block copolymer of polyethylene oxide and polypropylene oxide, with an average molecular weight of 1630. It exhibits antibacterial activity, inhibiting 56% of Mycobacterium avium at a concentration of 1 mg/mL. Poloxamer 122 L42 can form thermoreversible hydrogels and is employed as a food additive, and serves as a drug delivery carrier in cosmetics, pharmaceuticals, and tissue engineering.