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Anti-HAI-2/SPINT2 Antibody (5O92)
还可以产品编号 TMAY-03054
Anti-HAI-2/SPINT2 Antibody (5O92) 是一种 Rabbit 抗体，靶向 HAI-2/SPINT2。Anti-HAI-2/SPINT2 Antibody (5O92) 可用于 ELISA。
Anti-HAI-2/SPINT2 Antibody (5O92)
Anti-HAI-2/SPINT2 Antibody (5O92)
还可以产品编号 TMAY-03054
Anti-HAI-2/SPINT2 Antibody (5O92) 是一种 Rabbit 抗体，靶向 HAI-2/SPINT2。Anti-HAI-2/SPINT2 Antibody (5O92) 可用于 ELISA。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-HAI-2/SPINT2 Antibody (5O92) is a Rabbit antibody targeting HAI-2/SPINT2. Anti-HAI-2/SPINT2 Antibody (5O92) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 5O92 |
| 交叉反应 | Mouse |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse SPINT2 extracellular domain (rM SPINT2; TMPY-00926; NP_001076017.1; Met 1-Lys 140). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Choanal (CA) and gastrointestinal atresias (GA) are an important feature of syndromic congenital sodium diarrhea (sCSD), a disorder recently associated with mutations in the gene for serine protease inhibitor type 2 (SPINT2). The SPINT2 gene is epigenetically silenced or downregulated in human cancers, altering the balance of HGF activation/inhibition ratio, which contributes to cancer development and progression. SPINT2 is a tumor suppressor gene that inhibits proteases implicated in cancer progression, like HGFA, hepsin and matriptase. Loss of SPINT2 expression in tumors has been associated with gene promoter hypermethylation. SPINT2 (serine peptidase inhibitor Kunitz type 2), a proteolytic inhibitor of hepatocyte growth factor activator (HGFA), has a significant role in the suppression of the HGF-MET pathway and malignant melanoma progression. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Mouse SPINT2 protein (TMPY-00926) |
| 抗原种属 | Mouse |
| 研究领域 | Serine Proteases and Regulators |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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