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别名 ALF, ALBA, ALB2, afamin
Anti-AFM Antibody (5J767) 是一种 Rabbit 抗体,靶向 AFM。Anti-AFM Antibody (5J767) 可用于 ELISA。
Anti-AFM Antibody (5J767) 是一种 Rabbit 抗体,靶向 AFM。Anti-AFM Antibody (5J767) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 2,294 | 5日内发货 |
| 产品描述 | Anti-AFM Antibody (5J767) is a Rabbit antibody targeting AFM. Anti-AFM Antibody (5J767) can be used in ELISA. |
| 别名 | ALF, ALBA, ALB2, afamin |
| Ig Type | Rabbit IgG |
| 克隆号 | 5J767 |
| 反应种属 | Human |
| 特异性 | Human AFM |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human AFM / Afamin (rh AFM / Afamin ; TMPY-03962; P43652; Met1-Asn599). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Afamin is an 87 kDa glycoprotein with five predicted N-glycosylation sites. Afamin's glycan abundance contributes to conformational and chemical inhomogeneity presenting great challenges for molecular structure determination. Afamin, a human plasma glycoprotein and putative transporter of hydrophobic molecules, has been shown to act as extracellular chaperone for poorly soluble, acylated Wnt proteins, forming a stable, soluble complex with functioning Wnt proteins. The 2.1-Å crystal structure of glycosylated human afamin reveals an almost exclusively hydrophobic binding cleft capable of harboring large hydrophobic moieties. Afamin plays a role in anti-apoptotic cellular processes related to oxidative stress and is associated with insulin resistance and other features of metabolic syndrome. Afamin may serve as a new early biomarker for pathological glucose metabolism during pregnancy. And first trimester screening for pre-eclampsia could be provided by a combination of afamin and placental bed vascularization. Moreover, the combination of first trimester serum afamin levels with BMI could provide a possible screening for gestational diabetes mellitus. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human AFM / Afamin Protein (TMPY-03962) |
| 抗原种属 | Human |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
| 存储 | -20°C for 1 year |