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Anti-GBA3 Antibody-PE (1I463)
还可以产品编号 TMAY-01921P
Anti-GBA3 Antibody-PE (1I463) 是一种 PE-conjugated Mouse 抗体，靶向 GBA3。Anti-GBA3 Antibody-PE (1I463) 可用于 FCM。
Anti-GBA3 Antibody-PE (1I463)
Anti-GBA3 Antibody-PE (1I463)
还可以产品编号 TMAY-01921P
Anti-GBA3 Antibody-PE (1I463) 是一种 PE-conjugated Mouse 抗体，靶向 GBA3。Anti-GBA3 Antibody-PE (1I463) 可用于 FCM。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-GBA3 Antibody-PE (1I463) is a PE-conjugated Mouse antibody targeting GBA3. Anti-GBA3 Antibody-PE (1I463) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG2a |
| 克隆号 | 1I463 |
| 交叉反应 | Human |
| 验证活性 | Human GBA3 expression in Jurkat cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), and then stained with PE Mouse anti-GBA3. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | FCM |
| 推荐剂量 | 5 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human GBA3 (rh GBA3; TMPY-01579; NP_066024.1; Met1-Leu469) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | Cytosolic beta-glucosidase, also known as Cytosolic beta-glucosidase-like protein 1, GBA3, CBG and CBGL1 is a cytoplasm protein which belongs to theglycosyl hydrolase 1 family and Klotho subfamily. GBA3 / CBGL1 is a glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. GBA3 / CBGL1 is present in small intestine (at protein level). GBA3 / CBGL1 is expressed in liver, small intestine, colon, spleen and kidney. GBA3 / CBGL1 is down-regulated in renal cell carcinomas and hepatocellular carcinomas. GBA3 / CBGL1 is able to hydrolyze a broad variety of glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens. GBA3 / CBGL1 possesses beta-glycosylceramidase activity and may be involved in a nonlysosomal catabolic pathway of glycosylceramide. |
| 偶联 | PE |
| 免疫原 | Recombinant Human GBA3 protein (TMPY-01579) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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