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Anti-GPR84 Polyclonal Antibody
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产品编号 TMAB-00799
别名 Inflammation-related G-protein coupled receptor EX33, G-protein coupled receptor 84, GPR84, EX33
Anti-GPR84 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GPR84。Anti-GPR84 Polyclonal Antibody 可用于 WB。
Anti-GPR84 Polyclonal Antibody
Anti-GPR84 Polyclonal Antibody
还可以产品编号 TMAB-00799 别名 Inflammation-related G-protein coupled receptor EX33, G-protein coupled receptor 84, GPR84, EX33
Anti-GPR84 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GPR84。Anti-GPR84 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
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产品介绍
生物活性
抗原信息
化学信息
| 产品描述 | Anti-GPR84 Polyclonal Antibody is a Rabbit antibody targeting GPR84. Anti-GPR84 Polyclonal Antibody can be used in WB. |
| 疾病造模方案 | |
| 别名 | Inflammation-related G-protein coupled receptor EX33, G-protein coupled receptor 84, GPR84, EX33 |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat (predicted:Dog,Cow,Horse,Sheep,Monkey) |
| 验证活性 | 1. Sample: bone (Rat) Lysate at 40 μg Primary: Anti-GPR84 (TMAB-00799) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 44 kDa Observed band size: 44 kDa 2. Sample: SP2/0 (mouse) cell Lysate at 40 μg Lung (mouse) Lysate at 40 μg HL-60 (human) cell Lysate at 40 μg Muscle (mouse) Lysate at 40 μg Primary: Anti-GPR84 (TMAB-00799) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 44 kDa Observed band size: 44 kDa 3. Sample: Lane 1: Blood cell (Mouse) Lysate at 40 μg Lane 2: Lung (Mouse) Lysate at 40 μg Lane 3: Bone (Rat) Lysate at 40 μg Lane 4: Lung (Rat) Lysate at 40 μg Lane 5: Cerebrum (Rat) Lysate at 40 μg Lane 6: Cerebellum (Rat) Lysate at 40 μg Lane 7: U937 (Human) Cell Lysate at 30 μg Lane 8: U87MG (Human) Cell Lysate at 30 μg Lane 9: THP-1 (Human) Cell Lysate at 30 μg Primary: Anti-GPR84 (TMAB-00799) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 44 kDa Observed band size: 44 kDa |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 组织特异性 | Expressed predominantly in hematopoietic tissues. High levels detected in the bone marrow and lower levels in the peripheral leukocytes and lung. Also expressed in brain, heart, muscle, colon, thymus, spleen, kidney, liver, placenta and intestine. Within |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1 mg/mL |
| 研究背景 | G protein-coupled receptors (GPCRs), also designated seven transmembrane (7TM) receptors and heptahelical receptors, are a protein family which interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers such as diacylglycerol, cyclic AMP, inositol phosphates, and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling and are involved in many pathological conditions. G protein receptor 84 (GPR84), a member of the GCPR 1 family, is an orphan GCPR expressed in bone marrow, brain, heart, muscle, colon, thymus, spleen, kidney, liver, placenta, intestine, lung and peripheral blood leukocytes. In activated T cells, GPR84 regulates early interleukin-4 (IL-4) gene expression |
| 免疫原 | KLH conjugated synthetic peptide: human GPCR EX33/GPR84 |
| 抗原种属 | Human |
| 基因名称 | GPR84 |
| 基因ID | |
| 蛋白名称 | G-protein coupled receptor 84 |
| Uniprot ID | |
| 研究领域 | GPCR |
| 功能 | Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. May have important roles in processes from fatty acid metabolism to regulation of the immune system. |
| 分子量 | Theoretical: 44 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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