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Anti-SARS-CoV-2 (2019-nCoV) Spike S1 Polyclonal Antibody

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货号 TMAB-01662

别名 Surface glycoprotein, SPIKE_SARS2, Spike protein S1, Spike protein RBD, Spike glycoprotein, SARS-CoV-2 spike protein, 2019-nCOV Spike protein

Anti-SARS-CoV-2 (2019-nCoV) Spike S1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SARS-CoV-2 (2019-nCoV) Spike S1。Anti-SARS-CoV-2 (2019-nCoV) Spike S1 Polyclonal Antibody 可用于 ELISA。

Anti-SARS-CoV-2 (2019-nCoV) Spike S1 Polyclonal Antibody

Anti-SARS-CoV-2 (2019-nCoV) Spike S1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-01662 别名 Surface glycoprotein, SPIKE_SARS2, Spike protein S1, Spike protein RBD, Spike glycoprotein, SARS-CoV-2 spike protein, 2019-nCOV Spike protein

Anti-SARS-CoV-2 (2019-nCoV) Spike S1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SARS-CoV-2 (2019-nCoV) Spike S1。Anti-SARS-CoV-2 (2019-nCoV) Spike S1 Polyclonal Antibody 可用于 ELISA。

规格价格库存数量
100 μg
¥ 2,480
5日内发货
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产品介绍

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产品描述
Anti-SARS-CoV-2 (2019-nCoV) Spike S1 Polyclonal Antibody is a Rabbit antibody targeting SARS-CoV-2 (2019-nCoV) Spike S1. Anti-SARS-CoV-2 (2019-nCoV) Spike S1 Polyclonal Antibody can be used in ELISA.
别名Surface glycoprotein, SPIKE_SARS2, Spike protein S1, Spike protein RBD, Spike glycoprotein, SARS-CoV-2 spike protein, 2019-nCOV Spike protein
Ig Type
IgG
反应种属
(predicted:SARS-CoV-2)
应用ELISA
推荐剂量
ELISA: 1:5000-10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Virion membrane ; Single-pass type I membrane protein ; Host endoplasmic reticulum-Golgi intermediate compartment membrane ; Single-pass type I membrane protein ; Host cell membrane ; Single-pass type I membrane protein ;Note: Accumulates in the endoplasmic reticulum-Golgi intermediate compartment, where it participates in virus particle assembly. Colocalizes with S in the host endoplasmic reticulum-Golgi intermediate compartment. Some S oligomers are transported to the host plasma membrane, where they may mediate cell-cell fusion.
组织特异性The cytoplasmic Cys-rich domain is palmitoylated. Spike glycoprotein is digested within host endosomes.Specific enzymatic cleavages in vivo yield mature proteins. The precurssor is processed into S1 and S2 by host cell furin or another cellular protease t
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
抗原信息
免疫原
Recombinant Protein: SARS-CoV-2 Spike Protein S1
基因名称
S
蛋白名称
Spike glycoprotein
研究领域
SARS Coronavirus
功能
attaches the virion to the cell membrane by interacting with host receptor, initiating the infection (By similarity). Binding to human ACE2 receptor and internalization of the virus into the endosomes of the host cell induces conformational changes in the Spike glycoprotein (PubMed:32142651, PubMed:32075877, PubMed:32155444). Uses also human TMPRSS2 for priming in human lung cells which is an essential step for viral entry (PubMed:32142651). Proteolysis by cathepsin CTSL may unmask the fusion peptide of S2 and activate membranes fusion within endosomes.
化学信息
分子量Theoretical: 75/140 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

计算器

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