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Anti-Isocitrate dehydrogenase/IDH1 Antibody (9Q57)
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产品编号 TMAC-02246
别名 PICD, isocitrate dehydrogenase 1 (NADP+), soluble, IDPC, IDP, IDH, IDCD, HEL-S-26, HEL-216
Anti-Isocitrate dehydrogenase/IDH1 Antibody (9Q57) 是一种 Mouse 抗体，靶向 Isocitrate dehydrogenase/IDH1。Anti-Isocitrate dehydrogenase/IDH1 Antibody (9Q57) 可用于 WB,IHC。
Anti-Isocitrate dehydrogenase/IDH1 Antibody (9Q57)
Anti-Isocitrate dehydrogenase/IDH1 Antibody (9Q57)
还可以产品编号 TMAC-02246 别名 PICD, isocitrate dehydrogenase 1 (NADP+), soluble, IDPC, IDP, IDH, IDCD, HEL-S-26, HEL-216
Anti-Isocitrate dehydrogenase/IDH1 Antibody (9Q57) 是一种 Mouse 抗体，靶向 Isocitrate dehydrogenase/IDH1。Anti-Isocitrate dehydrogenase/IDH1 Antibody (9Q57) 可用于 WB,IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,995 | 5日内发货 | |
| 100 μL | ¥ 2,995 | 5日内发货 |
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| 产品描述 | Anti-Isocitrate dehydrogenase/IDH1 Antibody (9Q57) is a Mouse antibody targeting Isocitrate dehydrogenase/IDH1. Anti-Isocitrate dehydrogenase/IDH1 Antibody (9Q57) can be used in WB,IHC. |
| 别名 | PICD, isocitrate dehydrogenase 1 (NADP+), soluble, IDPC, IDP, IDH, IDCD, HEL-S-26, HEL-216 |
| 交叉反应 | Human,zebrafish |
| 验证活性 | 1. Western blot analysis of IDH1 on different cell lysates using anti-IDH1 antibody at 1/1000 dilution. Positive control: Lane 1: Hela, Lane 2: HepG2, Lane 3: A431, Lane 4: MCF-7, Lane 5: A549, Lane 6: Jurkat, Lane 7: Human kidney, Lane 8: Human brain, Lane 9: Human liver. 2. Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue using anti-IDH1 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human breast tissue using anti-IDH1 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-IDH1 antibody. Counter stained with hematoxylin. |
| 应用 | |
| 推荐剂量 | WB: 1:1000; IHC: 1:100-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Isocitrate dehydrogenase (IDH) is an enzyme that catalyzes the oxidative decarboxylation of isocitrate, producing alpha-ketoglutarate (α-ketoglutarate) and CO2. In humans, IDH exists in three isoforms: IDH3 catalyzes the third step of the citric acid cycle while converting NAD+ to NADH in the mitochondria. The isoforms IDH1 and IDH2 catalyze the same reaction outside the context of the citric acid cycle and use NADP+ as a cofactor instead of NAD+. They localize to the cytosol as well as the mitochondrion and peroxisome. Mutations in IDH1 are also implicated in cancer. Originally mutations in IDH1 were detected in an integrated genomic analysis of human glioblastoma multiforme. In addition to being mutated in diffuse gliomas, IDH1 has also been shown to harbor mutations in human acute myeloid leukemia (AML). |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 47 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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