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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-NADPH oxidase 4 Polyclonal Antibody

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货号 TMAB-09207

Anti-NADPH oxidase 4 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 NADPH oxidase 4。Anti-NADPH oxidase 4 Polyclonal Antibody 可用于 WB,ICC/IF,FCM。

Anti-NADPH oxidase 4 Polyclonal Antibody

Anti-NADPH oxidase 4 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-09207

Anti-NADPH oxidase 4 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 NADPH oxidase 4。Anti-NADPH oxidase 4 Polyclonal Antibody 可用于 WB,ICC/IF,FCM。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-NADPH oxidase 4 Polyclonal Antibody is a Rabbit antibody targeting NADPH oxidase 4. Anti-NADPH oxidase 4 Polyclonal Antibody can be used in WB,ICC/IF,FCM.
Ig Type
IgG
反应种属
Human
应用WBICC/IFFCM
推荐剂量
WB: 1:500-2000; ICC/IF: 1:100-500; FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell junction, focal adhesion. Cell membrane. Note=May localize to plasma membrane and focal adhesions.
组织特异性EXpressed in brain, in all layers of the cerebellum, in pyramidal cells of the Ammon horn and in Purkinje cells (at protein level). Expressed in osteoclasts, leukocytes, kidney, liver and lung.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Nox4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. Nox4 is also expressed in fetal tissues, placenta, glioblastoma and vascular cells. Like gp91-phox, the enzymatic activity of Nox4 produces superoxide anions. In vascular cells, the addition of angiotensin II increases Nox4 expression, which suggests a role for Nox-4 in vascular oxidative stress response.
抗原信息
免疫原
KLH conjugated synthetic peptide: human NOX4
抗原种属
Human
基因名称
NOX4
基因ID
50507
蛋白名称
NADPH oxidase 4
Uniprot ID
Q9NPH5
功能
Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.
化学信息
分子量Theoretical: 67 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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