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Anti-Angiopoietin 4 Polyclonal Antibody

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货号 TMAB-02546

Anti-Angiopoietin 4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Angiopoietin 4。Anti-Angiopoietin 4 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Angiopoietin 4 Polyclonal Antibody

Anti-Angiopoietin 4 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-02546

Anti-Angiopoietin 4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Angiopoietin 4。Anti-Angiopoietin 4 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
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100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-Angiopoietin 4 Polyclonal Antibody is a Rabbit antibody targeting Angiopoietin 4. Anti-Angiopoietin 4 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted (Probable).
组织特异性Highly expressed in the lung with much lower levels found in other tissues.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Angiopoietin 4 is a glycosylated protein with a fibrinogen C terminal domain. It is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. Angiopoietin 4 is a serum hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity and also acts as an apoptosis survival factor for vascular endothelial cells. It may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness. Decreased expression of this protein has been associated with type 2 diabetes. Alternatively spliced transcript variants encoding different isoforms have been described
抗原信息
免疫原
KLH conjugated synthetic peptide: human ANGPT4
抗原种属
Human
基因名称
ANGPT4
基因ID
蛋白名称
Angiopoietin-4
Uniprot ID
功能
Binds to TEK/TIE2, modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2. Promotes endothelial cell survival, migration and angiogenesis.
化学信息
分子量Theoretical: 54 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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