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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Insig2 Polyclonal Antibody

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货号 TMAB-07721

Anti-Insig2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Insig2。Anti-Insig2 Polyclonal Antibody 可用于 WB。

Anti-Insig2 Polyclonal Antibody

Anti-Insig2 Polyclonal Antibody

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货号 TMAB-07721

Anti-Insig2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Insig2。Anti-Insig2 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-Insig2 Polyclonal Antibody is a Rabbit antibody targeting Insig2. Anti-Insig2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Endoplasmic reticulum membrane; Multi-pass membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Insig2 is highly similar to the protein product encoded by gene Insig1. Both Insig1 protein and Insig2 protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Insig2
抗原种属
Human
基因名称
INSIG2
基因ID
51141
蛋白名称
Insulin-induced gene 2 protein
Uniprot ID
Q9Y5U4
功能
Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins (SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Seems to regulate the ubiquitin-mediated proteasomal degradation of HMGCR.
化学信息
分子量Theoretical: 25 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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