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别名 v-rel avian reticuloendotheliosis viral oncogene homolog A, p65, NFKB3
Anti-NF-kB p65 Antibody (9P885) 是一种 Mouse 抗体,靶向 NF-kB p65。Anti-NF-kB p65 Antibody (9P885) 可用于 IF,WB。
Anti-NF-kB p65 Antibody (9P885) 是一种 Mouse 抗体,靶向 NF-kB p65。Anti-NF-kB p65 Antibody (9P885) 可用于 IF,WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,345 | 5日内发货 | |
| 100 μL | ¥ 2,185 | 5日内发货 |
| 产品描述 | Anti-NF-kB p65 Antibody (9P885) is a Mouse antibody targeting NF-kB p65. Anti-NF-kB p65 Antibody (9P885) can be used in IF,WB. |
| 别名 | v-rel avian reticuloendotheliosis viral oncogene homolog A, p65, NFKB3 |
| 克隆号 | 9P885 |
| 交叉反应 | Human,Rat,Mouse |
| 验证活性 | 1. Western blot analysis of 1) Hela, 2) Rat Heart Tissue, 3) Mouse Spleen Tissue, using TMAC-02823 diluted at 1:2000. 2. IF analysis of Hela with TMAC-02823(Left) and DAPI (Right) diluted at 1:100. 3. 1 Input: Hela Cell Lysate, 2 IP product: IP dilute 1:200, Western blot analysis: primary antibody: TMAC-02823 1:2,000, Secondary antibody: Goat anti-Mouse IgG, Light chain specific, 1:5,000. ![]() ![]() ![]() |
| 应用 | IFWB |
| 推荐剂量 | WB: 1:1000-3000; IF: 1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Affinity purification using immunogen. |
| 性状 | Liquid |
| 缓冲液 | Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | NFkB p65 is ubiquitinated leading to its proteosomal degradation, which is required for termination of the NFkB response. Phosphorylation of NFkB p65 on S536 stimulates acetylation of K310 by CBP, enhancing transcriptional activity. NFkB p65 is also acetylated at K122, enhancing DNA binding and impairing the interaction with NFKBIA. The protein is deacetylated by HDAC3. Invasion of a host by a pathogen is frequently associated with the activation of NF-kB, which coordinates various aspects of immune function required for resistance to infection. |
| 偶联 | Unconjugated |
| Uniprot ID |
| 分子量 | Actual: 65 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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