GM-CSFR alpha Protein, Human, Recombinant (His) V2

Synonyms: 集落刺激因子, SMDP4, GMR, GM-CSF-R-α, GM-CSF-R-alpha, GMCSFR, GM-CSF Receptor α Protein, CSF2RY, CSF2RX, CSF2RAY, CSF2RAX, CSF2R, colony stimulating factor 2 receptor, α, low-affinity (granulocyte-macrophage), colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage), CDw116, CD116

规格

价格

库存

数量

5 μg

¥ 429

6-8日内发货

10 μg

¥ 697

6-8日内发货

20 μg

¥ 1,150

5日内发货

50 μg

¥ 2,260

5日内发货

100 μg

¥ 3,820

5日内发货

200 μg

¥ 6,680

5日内发货

500 μg

¥ 13,900

5日内发货

1 mg

¥ 24,900

5日内发货

生物活性

产品描述	GM-CSFR alpha Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is P15509.
生物活性	Measured by its ability to inhibit GM-CSF-dependent proliferation of TF‑1 human erythroleukemic cells.The ED50 for this effect is 0.5-2 μg/ml. (QC verified)
研究背景	Granulocyte-Macrophage Colony-Stimulating Factor Receptor Subunit α (CSF2RA) is a single-pass type I membrane protein which belongs to the type I cytokine receptor family of Type 5 subfamily. The CSF2RA gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes with some of the isoforms being membrane-bound and others being soluble. CSF2RA is a low affinity receptor for granulocyte-macrophage colony-stimulating factor. CSF2RA transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. Defects in CSF2RA are the cause of pulmonary surfactant metabolism dysfunction type 4 (SMDP4).
种属	Human
表达系统	HEK293 Cells
标签	C-6xHis
蛋白编号	P15509
蛋白构建	Glu23-Gly320
蛋白纯度	> 95% as determined by SDS-PAGE
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
复溶方法	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	集落刺激因子, SMDP4, GMR, GM-CSF-R-α, GM-CSF-R-alpha, GMCSFR, GM-CSF Receptor α Protein, CSF2RY, CSF2RX, CSF2RAY, CSF2RAX, CSF2R, colony stimulating factor 2 receptor, α, low-affinity (granulocyte-macrophage), colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage), CDw116, CD116
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	35.5 kDa (Predicted); 60 kDa (Reducing conditions)

储存&溶解度

运输方式	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
存储

GM-CSFR alpha Protein, Human, Recombinant (His) V2

GM-CSFR alpha Protein, Human, Recombinant (His) V2

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