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Anti-CDC123 Polyclonal Antibody

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货号 TMAB-04109

Anti-CDC123 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CDC123。Anti-CDC123 Polyclonal Antibody 可用于 FCM。

Anti-CDC123 Polyclonal Antibody

Anti-CDC123 Polyclonal Antibody

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货号 TMAB-04109

Anti-CDC123 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CDC123。Anti-CDC123 Polyclonal Antibody 可用于 FCM。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-CDC123 Polyclonal Antibody is a Rabbit antibody targeting CDC123. Anti-CDC123 Polyclonal Antibody can be used in FCM.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用FCM
推荐剂量
FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
组织特异性Widely expressed. Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes with the highest expression in testis.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Required for S phase entry of the cell cycle.The eukaryotic cell division cycle consists of a number of gene-controlled sequences that involve cyclin dependent kinases (Cdks) and cell division control (Cdc) proteins. Cdc123 (Cell division cycle protein 123), also known as D123, is a 336 amino acid cytoplasmic protein that is involved in cell cycle control. Widely expressed with high expression in thymus, spleen, ovary, testis, small intestine and leukocytes, Cdc123 functions to destabilize Chfr (checkpoint with forkhead and ring finger domain) proteins which, when accumulated, block the G to S phase transition. Cdc123 prevents the Chfr proteins from collecting in the cell, thereby allowing the cell to enter the S phase. Due to its role in cell cycle control, Cdc123 is thought to be a basal marker for luminal breast cancers.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CDC123/C10orf7
抗原种属
Human
基因名称
CDC123
基因ID
8872
蛋白名称
Cell division cycle protein 123 homolog
Uniprot ID
O75794
功能
Required for S phase entry of the cell cycle
化学信息
分子量Theoretical: 39 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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