购物车
  • 全部删除
  • TargetMol
    您的购物车当前为空
前往下单页继续购物
顶部生物活性储存和溶解信息计算器

Anti-CD71 Monoclonal Antibody

一键复制产品信息
Rating icon 很棒
产品编号 TMAZ-0133
别名 Transferrin receptor protein 1, T9, p90

Anti-CD71 Monoclonal Antibody is a humanized rabbit antibody targeting CD71. Anti-CD71 Monoclonal Antibody can be used in ELISA, FCM. 可用于 ELISA,FCM。

Anti-CD71 Monoclonal Antibody

Anti-CD71 Monoclonal Antibody

一键复制产品信息
Rating icon 很棒
产品编号 TMAZ-0133 别名 Transferrin receptor protein 1, T9, p90

Anti-CD71 Monoclonal Antibody is a humanized rabbit antibody targeting CD71. Anti-CD71 Monoclonal Antibody can be used in ELISA, FCM. 可用于 ELISA,FCM。

规格价格库存数量
10 μg
¥ 466
In stock
25 μg
¥ 761
7日内发货
50 μg
¥ 913
7日内发货
100 μg
¥ 1,277
7日内发货
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
选择批次:
浓度:0.71 mg/mL
联系我们获取更多批次信息
资源下载
COA产品操作手册

产品介绍

生物活性
产品描述
Anti-CD71 Monoclonal Antibody is a humanized rabbit antibody targeting CD71. Anti-CD71 Monoclonal Antibody can be used in ELISA,FCM.
别名Transferrin receptor protein 1, T9, p90
Ig Type
Rabbit monoclonal IgG
交叉反应
Human
验证活性
Flow cytometry analysis of Jurkat cells with TMAZ-0133BI, followed by goat anti-rabbit IgG-ABflo 647 (red). The isotype control is rabbit IgG (black line).
应用ELISAFCM
推荐剂量
0.1-0.2 μg/10E6 cells for FCM; 1 ng/μl for ELISA
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Single-pass type I membrane
构建方式This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of CD71 protein.
纯化方式Protein A Affinity Purified
性状Liquid
缓冲液0.22 μm filtered solution in PBS.
纯度> 95% as determined by SDS-PAGE.
研究背景Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes (PubMed: 26214738). Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the hereditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. Positively regulates T and B cell proliferation through iron uptake (PubMed: 26642240). Acts as a lipid sensor that regulates mitochondrial fusion by regulating activation of the JNK pathway (PubMed: 26214738). When dietary levels of stearate (C18: 0) are low, promotes activation of the JNK pathway, resulting in HUWE1-mediated ubiquitination and subsequent degradation of the mitofusin MFN2 and inhibition of mitochondrial fusion (PubMed: 26214738). When dietary levels of stearate (C18: 0) are high, TFRC stearoylation inhibits activation of the JNK pathway and thus degradation of the mitofusin MFN2 (PubMed: 26214738)|(Microbial infection) Acts as a receptor for new-world arenaviruses: Guanarito, Junin and Machupo virus
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Biotin
可提供抗体种类
2
抗原信息
免疫原
CD71
抗原种属
Human
基因ID
7037
Uniprot ID
P02786
研究领域
Cancer Research
化学信息
分子量150 kDa
颜色Transparent
物理性状Liquid
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器

评论列表

4个月前
5.0
Rating icon 很棒

评论内容

233
Related Tags: buy Anti-CD71 Monoclonal Antibody | purchase Anti-CD71 Monoclonal Antibody | Anti-CD71 Monoclonal Antibody cost | order Anti-CD71 Monoclonal Antibody | Anti-CD71 Monoclonal Antibody molecular weight