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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Neurotensin Receptor 1 Polyclonal Antibody

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货号 TMAB-09409

Anti-Neurotensin Receptor 1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Neurotensin Receptor 1。Anti-Neurotensin Receptor 1 Polyclonal Antibody 可用于 WB。

Anti-Neurotensin Receptor 1 Polyclonal Antibody

Anti-Neurotensin Receptor 1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-09409

Anti-Neurotensin Receptor 1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Neurotensin Receptor 1。Anti-Neurotensin Receptor 1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Neurotensin Receptor 1 Polyclonal Antibody is a Rabbit antibody targeting Neurotensin Receptor 1. Anti-Neurotensin Receptor 1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Multi-pass membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Neurotensin (NT) initiates an intracellular response by interacting with the G protein-coupled receptors NTR1 (NTS1 receptor, high affinity NTR) and NTR2 (NTS2 receptor, levocabastine-sensitive Neurotensin receptor), and the type I receptor NTR3 (NTS3 receptor, sortilin-1, Gp95). Neurotensin has a wide distribution in regions of the brain and in peripheral tissues where Neuro-tensin receptors can contribute to hypotension, hyperglycemia, hypothermia, antinociception and regulation of intestinal motility and secretion. HL-60 cells express NTR1, which can couple to Gq, Gi/o, or Gs. Alternative splicing of rat NTR2 can generate a five-transmembrane domain variant isoform that is co-expressed with the full-length NTR2 throughout the brain and spinal cord. NTR3 activation in the murine microglial cell line N11 induces MIP-2, MCP-1, IL-1b and TNFa in an ERK1/2- and Akt kinase-dependent manner.
抗原信息
免疫原
KLH conjugated synthetic peptide: human NTR1/Neurotensin Receptor 1
抗原种属
Human
基因名称
NTSR1
基因ID
4923
蛋白名称
Neurotensin receptor type 1
Uniprot ID
P30989
功能
Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. NTR1 has been reported in brain, pancreas, and small intestine. ESTs have been isolated from brain and colon libraries.
化学信息
分子量Theoretical: 46 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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