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顶部生物活性储存和溶解信息计算器

Anti-gp130/IL6ST Antibody (2B824)

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产品编号 TMAC-00654

别名 interleukin 6 signal transducer, IL-6RB, GP130, CDW130, CD130

Anti-gp130/IL6ST Antibody (2B824) 是一种 Mouse 抗体，靶向 gp130/IL6ST。Anti-gp130/IL6ST Antibody (2B824) 可用于 ICC,IHC,WB。

Anti-gp130/IL6ST Antibody (2B824)

Anti-gp130/IL6ST Antibody (2B824)

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产品编号 TMAC-00654 别名 interleukin 6 signal transducer, IL-6RB, GP130, CDW130, CD130

Anti-gp130/IL6ST Antibody (2B824) 是一种 Mouse 抗体，靶向 gp130/IL6ST。Anti-gp130/IL6ST Antibody (2B824) 可用于 ICC,IHC,WB。

规格价格库存数量
50 μL
¥ 1,995
5日内发货
100 μL
¥ 2,995
5日内发货
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产品介绍

生物活性
产品描述
Anti-gp130/IL6ST Antibody (2B824) is a Mouse antibody targeting gp130/IL6ST. Anti-gp130/IL6ST Antibody (2B824) can be used in ICC,IHC,WB.
别名interleukin 6 signal transducer, IL-6RB, GP130, CDW130, CD130
克隆号
2B824
交叉反应
Human
验证活性
1. Western blot analysis of CD130 on CD130 recombinant protein using anti-CD130 antibody at 1/5,000 dilution.
2. Western blot analysis of CD130 on Raji cell (1) and mouse lung tissue (2) lysates using anti-CD130 antibody at 1/500 dilution.
3. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-CD130 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human prostate tissue using anti-CD130 antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-CD130 antibody. Counter stained with hematoxylin.
6. Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-CD130 antibody. Counter stained with hematoxylin.
7. ICC staining CD130 (green) in HUVEC cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
8. ICC staining CD130 (green) in LOVO cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
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应用ICCIHCWB
推荐剂量
WB: 1:500-2000; IHC: 1:50-200; ICC: 1:50-200
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式ProG affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates Janus kinases. That causes phosphorylation of IL6ST tyrosine residues which in turn activates STAT3. Mediates signals which regulate immune response, hematopoiesis, pain control and bone metabolism. Has a role in embryonic development. Does not bind IL6. Essential for survival of motor and sensory neurons and for differentiation of astrocytes. Required for expression of TRPA1 in nociceptive neurons. Required for the maintenance of PTH1R expression in the osteoblast lineage and for the stimulation of PTH-induced osteoblast differentiation. Required for normal trabecular bone mass and cortical bone composition.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P40189
化学信息
分子量Theoretical: 103 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

GP-130GP 130CDW-130CDW 130CD-130CD 130

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