CD40 Protein, Mouse, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 45.4 kDa and the accession number is P27512-1.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
100 μg | ¥ 3,170 | 5日内发货 | ||
1 mg | ¥ 20,800 | 5日内发货 |
生物活性 | Testing in progress |
产品描述 | CD40 Protein, Mouse, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 45.4 kDa and the accession number is P27512-1. |
种属 | Mouse |
表达系统 | HEK293 Cells |
标签 | C-rFc |
蛋白编号 | P27512-1 |
别名 | HIGM1, IGM, IMD3, p50, GP39, T-BAM, Bp50, Tnfrsf5, TRAP, CD40 molecule, TNF receptor superfamily member 5, AI326936 |
蛋白构建 | The Mouse Cd40 ( NP_035741.2) (Met1-Arg193) was expressed with the Fc region of rabbit IgG at the C-terminus. |
蛋白纯度 | > 90 % as determined by SDS-PAGE. |
分子量 | 45.4 kDa (predicted) |
内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
存储 |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. |
研究背景 | CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 protein is expressed in B cells, dendritic cells, macrophages, endothelial cells, and several tumor cell lines. Defects in CD40 result in hyper-IgM immunodeficiency type 3 (HIGM3). In addition, CD40/CD40L interaction is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
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CD40 Protein, Mouse, Recombinant (rFc) HIGM 1 HIGM1 IGM IMD3 IMD-3 p50 IMD 3 GP39 GP 39 T-BAM Bp50 Tnfrsf5 HIGM-1 TRAP CD40 molecule, TNF receptor superfamily member 5 AI326936 AI 326936 AI-326936 GP-39 recombinant recombinant-proteins proteins protein