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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CARD14 Polyclonal Antibody

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货号 TMAB-03625

Anti-CARD14 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CARD14。Anti-CARD14 Polyclonal Antibody 可用于 WB,ICC/IF。

Anti-CARD14 Polyclonal Antibody

Anti-CARD14 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-03625

Anti-CARD14 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CARD14。Anti-CARD14 Polyclonal Antibody 可用于 WB,ICC/IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-CARD14 Polyclonal Antibody is a Rabbit antibody targeting CARD14. Anti-CARD14 Polyclonal Antibody can be used in WB,ICC/IF.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Dog,Pig,Cow,Horse,Sheep)
应用WBICC/IF
推荐剂量
WB: 1:500-2000; ICC/IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Isoform 1: Cytoplasm.Isoform 2: Cytoplasm.Isoform 3: Cytoplasm.
组织特异性Isoform 1 is detected in placenta and epidermal keratinocytes. Isoform 2 is detected in leukocytes and fetal brain.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein shares a similar domain structure with CARD11 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. Two alternatively spliced variants of this gene encoding distinct isoforms have been reported.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CARD14
抗原种属
Human
基因名称
CARD14
基因ID
79092
蛋白名称
Caspase recruitment domain-containing protein 14
Uniprot ID
Q9BXL6
功能
Plays a role in signaling mediated by TRAF2, TRAF3 and TRAF6 and protects cells against apoptosis. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10.
化学信息
分子量Theoretical: 113 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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