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TGF alpha Protein, Human, Recombinant
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很棒货号 TMPY-03958
别名 转化生长因子, transforming growth factor α, transforming growth factor alpha, TGF-α, TGFa, TFGA
The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared to adjacent normal tissue and high TGFA gene expression strongly correlated with poor survival in patients with lung adenocarcinoma, and miR-374a suppresses lung adenocarcinoma cell proliferation and invasion via targeting TGFA gene expression. Transforming growth factor alpha (TGFA) is a well-characterized mammalian growth factor that might contribute to the development of Cleft lip and palate (CL/P).
其他形式的 “TGF alpha Protein, Human, Recombinant”:
TGF alpha Protein, Human, Recombinant
一键复制产品信息 很棒货号 TMPY-03958 别名 转化生长因子, transforming growth factor α, transforming growth factor alpha, TGF-α, TGFa, TFGA
The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared to adjacent normal tissue and high TGFA gene expression strongly correlated with poor survival in patients with lung adenocarcinoma, and miR-374a suppresses lung adenocarcinoma cell proliferation and invasion via targeting TGFA gene expression. Transforming growth factor alpha (TGFA) is a well-characterized mammalian growth factor that might contribute to the development of Cleft lip and palate (CL/P).
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 396 | 3日内发货 | |
| 10 μg | ¥ 638 | 现货 | |
| 20 μg | ¥ 1,050 | 现货 | |
| 50 μg | ¥ 1,880 | 5日内发货 | |
| 100 μg | ¥ 2,930 | 5日内发货 | |
| 200 μg | ¥ 5,130 | 5日内发货 | |
| 500 μg | ¥ 10,800 | 5日内发货 | |
| 1 mg | ¥ 19,100 | 5日内发货 |
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产品介绍
生物活性
化学信息
储存&溶解度
| 产品描述 | The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared to adjacent normal tissue and high TGFA gene expression strongly correlated with poor survival in patients with lung adenocarcinoma, and miR-374a suppresses lung adenocarcinoma cell proliferation and invasion via targeting TGFA gene expression. Transforming growth factor alpha (TGFA) is a well-characterized mammalian growth factor that might contribute to the development of Cleft lip and palate (CL/P). |
| 生物活性 | 1.Measured by its binding ability in a functional ELISA. Immobilized Human TGF-alpha at 2 μg/ml (100 μl/well) can bind Human EGFR hFc, the EC50 of Human EGFR hFc is 80-500 ng/mL.
2. Measured in a cell proliferation assay using Balb/c 3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 0.5-2.5 ng/mL.   |
| 研究背景 | The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared to adjacent normal tissue and high TGFA gene expression strongly correlated with poor survival in patients with lung adenocarcinoma, and miR-374a suppresses lung adenocarcinoma cell proliferation and invasion via targeting TGFA gene expression. Transforming growth factor alpha (TGFA) is a well-characterized mammalian growth factor that might contribute to the development of Cleft lip and palate (CL/P). |
| 种属 | Human |
| 表达系统 | E. coli |
| 标签 | Tag Free |
| 蛋白编号 | P01135-1 |
| 蛋白构建 | A DNA sequence encoding the human TGFa (P01135-1) (Val40-Ala89) was expressed and purified. Predicted N terminal: Met |
| 蛋白纯度 | > 90 % as determined by SDS-PAGE  |
| 蛋白性状 | Lyophilized powder |
| 缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing 50 mM Tris, 100 mM NaCl, pH 8.0.Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| 复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| 别名 | 转化生长因子, transforming growth factor α, transforming growth factor alpha, TGF-α, TGFa, TFGA |
| 内毒素 | Please contact us for more information. |
| 分子量 | 5.6 kDa (predicted); 13 kDa (reducing conditions) |
| 颜色 | White |
| 物理性状 | Lyophilized powder |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. |
| 存储 | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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