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Anti-MYCBPAP Polyclonal Antibody

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货号 TMAB-09140

Anti-MYCBPAP Polyclonal Antibody 是一种 Rabbit 抗体,靶向 MYCBPAP。Anti-MYCBPAP Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-MYCBPAP Polyclonal Antibody

Anti-MYCBPAP Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-09140

Anti-MYCBPAP Polyclonal Antibody 是一种 Rabbit 抗体,靶向 MYCBPAP。Anti-MYCBPAP Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-MYCBPAP Polyclonal Antibody is a Rabbit antibody targeting MYCBPAP. Anti-MYCBPAP Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Membrane. Colocalizes with MYCBP in the cytoplasm.
组织特异性Expressed specifically in testis.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景AMAP-1 (AMY-1-binding protein 1), also known as AMAM-1 or MYCBPAP (MYCBP associated protein), is a 947 amino acid protein that is expressed specifically in testis and is involved in spermatogenesis and synaptic processes. AMAP-1 colocalizes with MYCBP (AMY-1) in cytoplasm and also localizes to membrane. The gene encoding AMAP-1 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
抗原信息
免疫原
KLH conjugated synthetic peptide: human MYCBPAP
抗原种属
Human
基因名称
MYCBPAP
基因ID
蛋白名称
MYCBP-associated protein
Uniprot ID
功能
May play a role in spermatogenesis. May be involved in synaptic processes.
化学信息
分子量Theoretical: 108 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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