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Anti-Cubilin Antibody (8J369)

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Anti-Cubilin Antibody (8J369)
产品编号 TMAC-01017
别名 MGA1, megaloblastic anemia 1, Intrinsic factor-vitamin B12 receptor, Intrinsic factor-cobalamin receptor, intrinsic factor B12-receptor, Intestinal intrinsic factor receptor, IFCR, CUBN_HUMAN, Cubn, Cubilin precursor, cubilin (intrinsic factor-cobalamin receptor), Cubilin, 460 kDa receptor

Anti-Cubilin Antibody (8J369) 是一种 Rabbit 抗体，靶向 Cubilin。Anti-Cubilin Antibody (8J369) 可用于 WB,IHC。

Anti-Cubilin Antibody (8J369)

Anti-Cubilin Antibody (8J369)

Rating icon 还可以
Anti-Cubilin Antibody (8J369)
产品编号 TMAC-01017 别名 MGA1, megaloblastic anemia 1, Intrinsic factor-vitamin B12 receptor, Intrinsic factor-cobalamin receptor, intrinsic factor B12-receptor, Intestinal intrinsic factor receptor, IFCR, CUBN_HUMAN, Cubn, Cubilin precursor, cubilin (intrinsic factor-cobalamin receptor), Cubilin, 460 kDa receptor

Anti-Cubilin Antibody (8J369) 是一种 Rabbit 抗体，靶向 Cubilin。Anti-Cubilin Antibody (8J369) 可用于 WB,IHC。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-Cubilin Antibody (8J369) is a Rabbit antibody targeting Cubilin. Anti-Cubilin Antibody (8J369) can be used in WB,IHC.
别名MGA1, megaloblastic anemia 1, Intrinsic factor-vitamin B12 receptor, Intrinsic factor-cobalamin receptor, intrinsic factor B12-receptor, Intestinal intrinsic factor receptor, IFCR, CUBN_HUMAN, Cubn, Cubilin precursor, cubilin (intrinsic factor-cobalamin receptor), Cubilin, 460 kDa receptor
Ig Type
IgG
克隆号
8J369
交叉反应
Human
验证活性
1. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Cubilin antibody. Counter stained with hematoxylin.
应用
WB
IHC
推荐剂量
WB: 1:500; IHC: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Cotransporter which plays a role in lipoprotein, vitamin and iron metabolism, by facilitating their uptake. Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the GIF-cobalamin complex. The binding of all ligands requires calcium. Serves as important transporter in several absorptive epithelia, including intestine, renal proximal tubules and embryonic yolk sac. Interaction with LRP2 mediates its trafficking throughout vesicles and facilitates the uptake of specific ligands like GC, hemoglobin, ALB, TF and SCGB1A1. Interaction with AMN controls its trafficking to the plasma membrane and facilitates endocytosis of ligands. May play an important role in the development of the peri-implantation embryo through internalization of APOA1 and cholesterol. Binds to LGALS3 at the maternal-fetal interface.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
O60494
化学信息
分子量Theoretical: 399 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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