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TREM-2 Protein, Human, Recombinant (mFc)

TREM-2 Protein, Human, Recombinant (mFc)

产品编号 TMPJ-00117
别名: Triggering receptor expressed on myeloid cells 2, Triggering receptor expressed on monocytes 2, TREM-2, TREM2

TREM-2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 50-65 KDa and the accession number is Q9NZC2.

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TREM-2 Protein, Human, Recombinant (mFc)
规格 价格/CNY 货期 数量
10 μg ¥ 550 5日内发货
50 μg ¥ 1,670 5日内发货
500 μg ¥ 13,700 5日内发货
1 mg ¥ 20,500 5日内发货
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产品目录号及名称: TREM-2 Protein, Human, Recombinant (mFc) (TMPJ-00117)
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产品描述 TREM-2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 50-65 KDa and the accession number is Q9NZC2.
种属 Human
表达系统 HEK293 Cells
标签 C-mFc
蛋白编号 Q9NZC2
别名 Triggering receptor expressed on myeloid cells 2, Triggering receptor expressed on monocytes 2, TREM-2, TREM2
氨基酸序列 His19-Ser174
蛋白构建 His19-Ser174
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 50-65 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法 Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 TREM2 is a cell surface receptor of the immunoglobulin superfamily. TREM2 is a type-1 transmembrane protein that shuttles to the plasma membrane where it exerts its cell autonomous biological functions. TREM2 undergoes regulated intramembrane proteolysis (RIP). TREM2 is preferentially expressed in microglia and is functionally required for migration, cytokine release, phagocytosis, lipid sensing, ApoE binding, shielding of amyloid plaques, and microglia proliferation in the brian. Most of the functionally investigated mutations are located within the Ig-like domain of TREM2.

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Keywords

TREM-2 Protein, Human, Recombinant (mFc) Triggering receptor expressed on myeloid cells 2 Triggering receptor expressed on monocytes 2 TREM-2 TREM 2 TREM2 recombinant recombinant-proteins proteins protein

 

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