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Anti-NFAT2 Antibody (6M348)

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货号 TMAB-09425

Anti-NFAT2 Antibody (6M348) 是一种 Rabbit 抗体，靶向 NFAT2。Anti-NFAT2 Antibody (6M348) 可用于 WB,ICC/IF,FCM。

Anti-NFAT2 Antibody (6M348)

Anti-NFAT2 Antibody (6M348)

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Rating icon 还可以
货号 TMAB-09425

Anti-NFAT2 Antibody (6M348) 是一种 Rabbit 抗体，靶向 NFAT2。Anti-NFAT2 Antibody (6M348) 可用于 WB,ICC/IF,FCM。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-NFAT2 Antibody (6M348) is a Rabbit antibody targeting NFAT2. Anti-NFAT2 Antibody (6M348) can be used in WB,ICC/IF,FCM.
Ig Type
IgG
克隆号
6M348
反应种属
Human
应用WBICC/IFFCM
推荐剂量
WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustained and transient calcium signals. The subcellular localization of NFATC plays a key role in the regulation of gene transcription.
组织特异性Expressed in thymus, peripheral leukocytes as T-cells and spleen. Isoforms A are preferentially expressed in effector T-cells (thymus and peripheral leukocytes) whereas isoforms B and isoforms C are preferentially expressed in naive T-cells (spleen). Isoforms B are expressed in naive T-cells after first antigen exposure and isoforms A are expressed in effector T-cells after second antigen exposure.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells.
抗原信息
免疫原
A synthesized peptide: human NFAT2
抗原种属
Human
基因名称
NFATC1
基因ID
4772
蛋白名称
Nuclear factor of activated T-cells, cytoplasmic 1
Uniprot ID
O95644
功能
Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells.Required for osteoclastogenesis and regulates many genes important for osteoclast differentiation and function.
化学信息
分子量Theoretical: 101 kDa. Actual: 101 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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