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Anti-GPR58 Polyclonal Antibody

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货号 TMAB-06726

Anti-GPR58 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 GPR58。Anti-GPR58 Polyclonal Antibody 可用于 WB。

Anti-GPR58 Polyclonal Antibody

Anti-GPR58 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-06726

Anti-GPR58 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 GPR58。Anti-GPR58 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-GPR58 Polyclonal Antibody is a Rabbit antibody targeting GPR58. Anti-GPR58 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Pig,Cow,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Integral membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Trace amines are endogenous molecules structurally related to classical biogenic amines that are linked to psychiatric conditions. A family of G-protein coupled receptors referred to as trace-amine-associated receptors (TAAR) are activated by trace amines and are present in very low levels in mammalian tissue. TAAR’s contain several structural features that are similar to the rhodopsin beta-adrenergic receptor superfamily, including the positions of the seven transmembrane regions that provide common ligand-binding pockets as well as the short N- and C-terminal domains. TAAR proteins are potential targets for drugs of abuse, such as amphetamine and MDMA, as well as neuropsychiatric disorders including schizophrenia, depression, and attention deficit disorder. TAAR-1 is a 340 amino acid protein that increases intracellular cAMP accumulation in response to beta-phenylethylamine and tyramine. TAAR-1 is associated with the detection of social cues, illustrating its significance as a therapeutic target.
抗原信息
免疫原
KLH conjugated synthetic peptide: human GPR58
抗原种属
Human
基因名称
TAAR2
基因ID
蛋白名称
Trace amine-associated receptor 2
Uniprot ID
功能
G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. GPCR GPR58 is a member of this family (subfamily Orphan-A). GPR58 expression has not been reported from human liver and several brain areas.
化学信息
分子量Theoretical: 40 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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