Anti-AMPK beta 1 Antibody (6A384) is a Rabbit antibody targeting AMPK beta 1. Anti-AMPK beta 1 Antibody (6A384) can be used in WB,FCM.

IgG

6A384

Human,Mouse (predicted:Rat)

WB: 1:500-2000; FCM: 1:50-100

Monoclonal

A synthesized peptide: human AMPK beta 1

Human

PRKAB1

5'-AMP-activated protein kinase subunit beta-1

Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).