Anti-NTH1 Antibody (7B232) is a Rabbit antibody targeting NTH1. Anti-NTH1 Antibody (7B232) can be used in WB.

IgG

7B232

Human

25 ug total protein per lane of various lysates (see on figure) probed with NTH1 monoclonal antibody, unconjugated (TMAB-09659) at 1: 1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.

WB=1:500-2000

Monoclonal

A synthesized peptide: human NTH1

Human

NTHL1

Endonuclease III-like protein 1

Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. Has also 8-oxo-7,8-dihydroguanine (8-oxoG) DNA glycosylase activity. Acts preferentially on DNA damage opposite guanine residues in DNA. Is able to process lesions in nucleosomes without requiring or inducing nucleosome disruption.