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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-NTH1 Antibody (7B232)

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货号 TMAB-09659

Anti-NTH1 Antibody (7B232) 是一种 Rabbit 抗体，靶向 NTH1。Anti-NTH1 Antibody (7B232) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

Anti-NTH1 Antibody (7B232)

Anti-NTH1 Antibody (7B232)

一键复制产品信息
Rating icon 还可以
货号 TMAB-09659

Anti-NTH1 Antibody (7B232) 是一种 Rabbit 抗体，靶向 NTH1。Anti-NTH1 Antibody (7B232) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-NTH1 Antibody (7B232) is a Rabbit antibody targeting NTH1. Anti-NTH1 Antibody (7B232) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG
克隆号
7B232
反应种属
Human
应用WBIHC-PIHC-FrICC/IFIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; ICC/IF: 1:50-200; IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Widely expressed with highest levels in heart and lowest levels in lung and liver.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Has both an apurinic and/or apyrimidinic endonuclease activity and a DNA N-glycosylase activity. Incises damaged DNA at cytosines, thymines and guanines. Acts on a damaged strand, 5' from the damaged site. Required for the repair of both oxidative DNA damage and spontaneous mutagenic lesions.
抗原信息
免疫原
A synthesized peptide: human NTH1
抗原种属
Human
基因名称
NTHL1
基因ID
4913
蛋白名称
Endonuclease III-like protein 1
Uniprot ID
P78549
功能
Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. Has also 8-oxo-7,8-dihydroguanine (8-oxoG) DNA glycosylase activity. Acts preferentially on DNA damage opposite guanine residues in DNA. Is able to process lesions in nucleosomes without requiring or inducing nucleosome disruption.
化学信息
分子量Theoretical: 34 kDa. Actual: 34 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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