D-Mannopyranose

Name: D-Mannopyranose
Brand: TargetMol
SKU: T0592
Price: 118 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 99.84%

货号 T0592Cas号 530-26-7

别名 D-吡喃甘露糖

D-Mannopyranose 是一种己糖或可发酵单糖，是甘露糖、水曲柳和相关植物的葡萄糖异构体。

D-Mannopyranose

一键复制产品信息

很棒

纯度: 99.84%

货号 T0592 别名 D-吡喃甘露糖Cas号 530-26-7

D-Mannopyranose 是一种己糖或可发酵单糖，是甘露糖、水曲柳和相关植物的葡萄糖异构体。

规格	价格	库存
2 mg	¥ 118	现货
5 mg	¥ 167	现货
10 mg	¥ 226	现货
25 mg	¥ 350	现货
50 mg	¥ 480	现货
100 mg	¥ 870	现货
500 mg	¥ 2,150	现货
1 mL x 10 mM (in DMSO)	¥ 240	现货

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产品介绍

D-Mannopyranose AI Summary

D-Mannopyranose exhibits diverse bioactivities across multiple assays. It inhibits Mannosidase in jack bean (Canavalia ensiformis) with an IC50 of approximately 20,000,000 nM and shows inhibition towards Human acrosin with 60.0% inhibition by aldohexoses and 48.0% by aldoses. It also displays inhibitory activity against mannan binding relative to Concanavalin A with an IC50 of 5,300,000 nM determined by a quartz crystal microbalance assay. The compound demonstrates anticryptosporidial activity against Cryptosporidium parvum GCH1 and Cryptosporidium hominis TU502, inhibiting hemagglutination of rabbit erythrocytes with MIC values of 50,000,000 nM and >100,000,000 nM, respectively. Additionally, it inhibits Cryptosporidium parvum Galactose/N-acetylgalactosamine-specific lectin binding to Caco2A cells with an IC50 >500,000,000 nM. It shows bioactivity in Drosophila melanogaster GM2b and LM408 with less than 10.0% inhibition at 5 mM concentrations. Binding affinity to Concanavalin A is indicated by an IC50 of 10,456,000 nM, with a competitive binding ratio to methyl alpha-D-mannoside of 0.13. D-Mannopyranose also shows inhibitory effects on delayed death of the malarial parasite plastid at 18,526 nM, HP1-beta Chromodomain interactions at 100,000 nM, Polymerase Kappa at 13,371.4 nM, and ERG Ets/DNA interaction at 50,118.7 nM. It inhibits biotinylated-TM PAA from various human receptors and Escherichia coli FimH, showing over 90% inhibition after 3 hours. The compound has a Ki of 13,100,000 nM for [125I]-Man30-BSA displacement from the DC-SIGN receptor carbohydrate recognition domain and an IC50 of 560,000 nM for inhibiting E. coli FimH yeast agglutination. Furthermore, D-Mannopyranose binds Burkholderia cenocepacia J2315 BC2L-A with a Kd of 5,150 nM, displacing N-(fluorescein-5-yl)-N'-(alpha-D-mannopyranosyloxyethyl)-thiocarbamide with an IC50 of 10,800 nM. Surface plasmon resonance assays show binding to Jack bean Concanavalin A with a Kd of 200,000 nM. It inhibits Pseudomonas aeruginosa PAO1 LecB with an IC50 of 149,000 nM and PA14 LecB with an IC50 of 52,000 nM based on fluorescence polarization assays. Lastly, it inhibits FIBCD1 V5-His tagged ecto-domain binding to acetylated BSA in ELISA with less than 50.0% inhibition at 50 mM..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	D-Mannopyranose is a hexose or fermentable monosaccharide and isomer of glucose from manna, the ash Fraxinus ornus and related plants.
别名	D-吡喃甘露糖

化学信息

分子量	180.17
分子式	C₆H₁₂O₆
CAS No.	530-26-7
Smiles	C([C@@H]1[C@H]([C@@H]([C@@H](C(O1)O)O)O)O)O
密度	1.732 g/cm3 (Predicted)

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 131 mg/mL (727.09 mM), Sonication is recommended.

H2O: 33.33 mg/mL (184.99 mM), Sonication is recommended.

溶液配制表

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	5.5503 mL	27.7516 mL	55.5031 mL	277.5157 mL
5 mM	1.1101 mL	5.5503 mL	11.1006 mL	55.5031 mL
10 mM	0.5550 mL	2.7752 mL	5.5503 mL	27.7516 mL
20 mM	0.2775 mL	1.3876 mL	2.7752 mL	13.8758 mL
50 mM	0.1110 mL	0.5550 mL	1.1101 mL	5.5503 mL
100 mM	0.0555 mL	0.2775 mL	0.5550 mL	2.7752 mL