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Anti-ARS2 Polyclonal Antibody

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货号 TMAB-02846

Anti-ARS2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ARS2。Anti-ARS2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-ARS2 Polyclonal Antibody

Anti-ARS2 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-02846

Anti-ARS2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ARS2。Anti-ARS2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-ARS2 Polyclonal Antibody is a Rabbit antibody targeting ARS2. Anti-ARS2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Dog,Pig,Cow,Horse)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm.
组织特异性Ubiquitously expressed.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景ARS2(Arsenite resistance protein 2) confers arsenite resistance. The protein belongs to the ARS2 family. Arsenic is a human carcinogen whose mechanism of action is unknown. The arsenite acts as a comutagen by interfering with DNA repair. Two genes, ASR1(Arsenite resistance protein 1) and ASR2 (Arsenite resistance protein 2), confer arsenite resistance to arsenite-sensitive cells. ASR1 shows almost complete homology with the rat fau gene, a tumor suppressor gene which contains a ubiquitin like region fused to S30 ribosomal protein. Arsenite inhibits ubiquitin dependent proteolysis. The tumor suppressor fau gene product or some other aspect of the ubiquitin system may be a target for arsenic toxicity and that disruption of the ubiquitin system may contribute to the genotoxicity and carcinogenicity of arsenite.
抗原信息
免疫原
KLH conjugated synthetic peptide: human ARS2
抗原种属
Human
基因名称
SRRT
基因ID
蛋白名称
Serrate RNA effector molecule homolog
Uniprot ID
化学信息
分子量Theoretical: 101 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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