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Anti-CD83 Antibody (8S678) 是一种 Rabbit 抗体,靶向 CD83。Anti-CD83 Antibody (8S678) 可用于 WB。
Anti-CD83 Antibody (8S678) 是一种 Rabbit 抗体,靶向 CD83。Anti-CD83 Antibody (8S678) 可用于 WB。
产品描述 | Anti-CD83 Antibody (8S678) is a Rabbit antibody targeting CD83. Anti-CD83 Antibody (8S678) can be used in WB. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 8S678 |
交叉反应 | Human |
验证活性 | Anti-CD83 rabbit monoclonal antibody at 1:500 dilution. -Lane A: Jurkat Whole Cell Lysate. -Lane B: 293T Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:23 kDa. -Observed band size:55 kDa |
应用 | WB |
推荐剂量 | WB: 1:500-1:2000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD83 (rh CD83; TMPY-01829; Q01151-1; Met1-Ala143). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD83 is considered as a marker of mature dendritic cells as well as an adhesion receptor that binds to resting monocytes and a subset of activated CD8+T cells. In certain conditions, CD83 tended to dimerize or even multimerize through its aberrant intermolecular disulfide bonds. The injection of CD83-Ig can significantly enhance the rate of tumor growth and inhibit the T cell growth. |
偶联 | Unconjugated |
免疫原 | Recombinant Human CD83 Protein (TMPY-01829) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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