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Anti-Aromatase/CYP19A1 Antibody (3T740)

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Anti-Aromatase/CYP19A1 Antibody (3T740)
产品编号 TMAC-00272

Anti-Aromatase/CYP19A1 Antibody (3T740) 是一种 Rabbit 抗体,靶向 Aromatase/CYP19A1。Anti-Aromatase/CYP19A1 Antibody (3T740) 可用于 WB,IP。

Anti-Aromatase/CYP19A1 Antibody (3T740)

Anti-Aromatase/CYP19A1 Antibody (3T740)

Rating icon 还可以
Anti-Aromatase/CYP19A1 Antibody (3T740)
产品编号 TMAC-00272

Anti-Aromatase/CYP19A1 Antibody (3T740) 是一种 Rabbit 抗体,靶向 Aromatase/CYP19A1。Anti-Aromatase/CYP19A1 Antibody (3T740) 可用于 WB,IP。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-Aromatase/CYP19A1 Antibody (3T740) is a Rabbit antibody targeting Aromatase/CYP19A1. Anti-Aromatase/CYP19A1 Antibody (3T740) can be used in WB,IP.
Ig Type
IgG
交叉反应
Human,Rat
验证活性
1. Western blot analysis of Aromatase on different cells lysates using anti-Aromatase antibody at 1/500 dilution. Positive control: Lane 1: JAR, Lane 2: Jurkat.
应用
推荐剂量
WB: 1:500-2000; IP: 1:10-50
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景P450 enzymes constitute a family of monooxygenase enzymes that are involved in the metabolism of a wide array of endogenous and xenobiotic compounds. P450 enzymes can be classified, based on their sequence similarities, into distinct subfamilies, which include CYP1A and CYP2A. Other P450 family members include CYP19, also designated aromatase (P450arom), which catalyzes the conversion of C19 steroids to estrogens in various tissues, including placenta, gonads, adipose tissue, skin and brain. CYP19 expression is controlled by hormonally regulated promoters in different tissues and increased CYP19 activity is associated with familial gynecomastia. Also, a polymorphic allele of CYP19 (repeat (TTTA)12) is present in a majority of breast cancer patients. P450 cholesterol 7α-hydroxylase, CYP7A1, is the rate-limiting enzyme of bile acid synthesis in the liver, and its expression is mediated by the bile acid receptor FXR. CYP27A1 catalyzes vitamin D3 25-hydroxylation and is localized to the mitochondria in kidney and liver.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 58 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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