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Anti-Plectin Antibody (4J312) 是一种 Rabbit 抗体,靶向 Plectin。Anti-Plectin Antibody (4J312) 可用于 WB,IHC,IP。
Anti-Plectin Antibody (4J312) 是一种 Rabbit 抗体,靶向 Plectin。Anti-Plectin Antibody (4J312) 可用于 WB,IHC,IP。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,495 | 5日内发货 | |
100 μL | ¥ 2,485 | 5日内发货 |
产品描述 | Anti-Plectin Antibody (4J312) is a Rabbit antibody targeting Plectin. Anti-Plectin Antibody (4J312) can be used in WB,IHC,IP. |
别名 | PLTN, Plectin-1, Plectin 6, Plectin 1 intermediate filament binding protein 500kDa, Plectin 1, Plectin, PLEC1b, PLEC1, PLEC_HUMAN, pleC, PCN, Hemidesmosomal protein 1, HD1, EBSO, EBS1 |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Immunohistochemical analysis of paraffin-embedded rat skeletal muscle tissue using anti-Plectin antibody. Counter stained with hematoxylin. 2. Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue using anti-Plectin antibody. Counter stained with hematoxylin. |
应用 | |
推荐剂量 | WB: 1:1000; IHC: 1:100-500 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Plectin is an abundant cytoskeletal protein that is involved in cytoplasm stabilization. Plectin has been shown to crosslink intermediate filaments to microtubules and microfilaments, and to anchor intermediate filaments to the plasma and nuclear membranes. Plectin binds both Lamin B and vimentin, and this binding is regulated by a variety of protein kinases. Phosphorylation by PKA or PKC results in decreased binding to Lamin B, and phosphorylation by PKA enhances the plectin-vimentin interactions. Plectin is also a substrate for p34cdc2 kinase. Several alternative splice isoforms of plectin are known to exist. Mutations in human plectin are known to cause epidermolysis bullosa simplex with muscular dystrophy (EBS-MD). |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 531 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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