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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CK10 Polyclonal Antibody

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货号 TMAB-04381

Anti-CK10 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CK10。Anti-CK10 Polyclonal Antibody 可用于 ICC/IF,FCM。

Anti-CK10 Polyclonal Antibody

Anti-CK10 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-04381

Anti-CK10 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CK10。Anti-CK10 Polyclonal Antibody 可用于 ICC/IF,FCM。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-CK10 Polyclonal Antibody is a Rabbit antibody targeting CK10. Anti-CK10 Polyclonal Antibody can be used in ICC/IF,FCM.
Ig Type
IgG
反应种属
Human
应用ICC/IFFCM
推荐剂量
ICC/IF: 1:100-500; FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
组织特异性Seen in all suprabasal cell layers including stratum corneum.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Cytokeratin 10 is a heterotetramer of two type I and two type II keratins. Cytokeratin 10 is generally associated with keratin 1. It is seen in all suprabasal cell layers including stratum corneum. A number of alleles are known that mainly differ in the Gly-rich region (positions 490-560). Defects in cytokeratin 10 are a cause of epidermolytic hyperkeratosis (EHK), also known as bullous congenital ichthyosiform erythroderma (BCIE) or bullous erythroderma ichthyosiformis congenita of Brocq. EHK is an hereditary skin disorder characterized by blistering and a marked thickening of the stratum corneum. At birth, affected individuals usually present with redness, blisters and superficial erosions due to cytolysis. Within a few weeks, the erythroderma and blister formation diminish and hyperkeratoses develop. Transmission is autosomal dominant, but most cases are sporadic. Defects in cytokeratin 10 are also a cause of annular epidermolytic ichthyosis (AEI), also known as cyclic ichthyosis with epidermolytic hyperkeratosis. AEI resembles clinical and histologic features of both epidermolytic hyperkeratosis and ichthyosis bullosa of Siemens.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CK10
抗原种属
Human
基因名称
KRT10
基因ID
3858
蛋白名称
Keratin, type I cytoskeletal 10
Uniprot ID
P13645
化学信息
分子量Theoretical: 56 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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