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Anti-FASP1 Polyclonal Antibody

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货号 TMAB-05905

Anti-FASP1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FASP1。Anti-FASP1 Polyclonal Antibody 可用于 WB。

Anti-FASP1 Polyclonal Antibody

Anti-FASP1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-05905

Anti-FASP1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FASP1。Anti-FASP1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-FASP1 Polyclonal Antibody is a Rabbit antibody targeting FASP1. Anti-FASP1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Horse,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Centromere.
组织特异性Detected in testis.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Mapping to chromosome 21, the FASP1 gene (FAPP1-associated protein 1) encodes a 233 amino acid protein that is homologous to the fission yeast protein Mis18. In yeast, Mis18 is localized to the centrosome and forms a complex with Mis16 to maintain the deacetylated state of histones specifically in the central core of centromeres. FASP1, also known as Protein Mis18-alpha and C21orf45, is required for the recruitment of CENP-A to centrosomes and is thereby essential for normal chromosome segregation during mitosis. With expression in testis, FASP1 exists as a homodimer, a heterodimer with MIS18B or is present in a complex containing other Mis18 family members. FASP1 has been shown to bind to pp5644 in Hela cells, where overexpression of pp5644 leads to inhibited growth and colony formation.
抗原信息
免疫原
KLH conjugated synthetic peptide: human FASP1/C21orf45
抗原种属
Human
基因名称
MIS18A
基因ID
蛋白名称
Protein Mis18-alpha
Uniprot ID
功能
Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
化学信息
分子量Theoretical: 26 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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