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- 9019种肿瘤相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
- 产品经过临床验证和临床实验，具有生物安全保障和一定的生物活性；
- 是肿瘤发生机理研究、抗肿瘤药物筛选的有效工具；?
- 靶点含PI3K、HDAC、mTOR、CDK、Aurora Kinase、JAK等；
- 结构多样，药效显著，可渗透细胞；
- 详细的说明书，化合物结构、靶点信息、IC50值、活性描述等；
- NMR、HPLC/LCMS检测技术保证产品高纯度和高质量，减少假阳性发生概率。
抗癌化合物库
Anti-Cancer Compound Library
很棒在过去的几十年中癌症的研究和治疗取得了巨大的成功，但癌症仍然是人类面临的巨大挑战，给患者身心健康带来巨大的痛苦。癌细胞具有许多显著不同的生物学特征，表现出无限的增殖潜能，维持自身生长信号的持续稳定，逃避应激信号(例如治疗药物)诱导的细胞凋亡，刺激血管生长，为肿瘤提供营养，同时逃避免疫系统防御和诱导局部慢性炎症，发挥其侵袭和转移能力，表现出异常的代谢活动，并通过突变和表观遗传机制显著改变全基因组的稳定性。 我们根据上述癌细胞显著不同的特征和异常的代谢活动，精心筛选了 9019 个肿瘤相关的小分子化合物，这些化合物都是调节肿瘤细胞代谢、增殖、侵袭、转移通路上的小分子，可用于肿瘤相关的研究以及抗肿瘤药物的筛选，可用于高通量、高内涵筛选。
TargetMol 的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。
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化合物库相关信息
Excel
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抗癌化合物库规格
- 1 mg
- 30 μL x 10 mM (in DMSO)
- 50 μL x 10 mM (in DMSO)
- 100 μL x 10 mM (in DMSO)
- 250 μL x 10 mM (in DMSO)
询价 & 定制
产品描述
包装和储存
- 可选用DMSO耐受的96/384孔板或2D 条形码编码管；
- 干粉蓝冰运输，DMSO溶液干冰运输；
- 排布：96孔板：1st & 12th 空白对照，384孔板：1st & 2nd & 23th & 24th空白对照。
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化合物库组成
Apoptosis
Autophagy
5-HT Receptor
Endogenous Metabolite
Antibacterial
NF-κB
COX
DNA/RNA Synthesis
Adrenergic Receptor
CDK
Dopamine Receptor
PI3K
EGFR
Potassium Channel
Reactive Oxygen Species
Calcium Channel
Histamine Receptor
VEGFR
Antibiotic
Cytochromes P450
Sodium Channel
HDAC
GABA Receptor
Parasite
PPAR
TRP/TRPV Channel
mTOR
Akt
GPR
AChR
ERK
JAK
Antifungal
Wnt/beta-catenin
Src
HIV Protease
Prostaglandin Receptor
FLT
Estrogen Receptor/ERR
PARP
STAT
p38 MAPK
Adenosine Receptor
Opioid Receptor
PDGFR
Microtubule Associated
AMPK
Dehydrogenase
GSK-3
Nucleoside Antimetabolite/Analog
Topoisomerase
FGFR
Raf
TNF
Caspase
Epigenetic Reader Domain
iGluR
Bcl-2 Family
Estrogen/progestogen Receptor
Influenza Virus
Antioxidant
Glucocorticoid Receptor
c-Met/HGFR
Androgen Receptor
c-Kit
Histone Methyltransferase
Ferroptosis
Bcr-Abl
HSP
Cannabinoid Receptor
PKC
MMP
ATPase
ALK
Sirtuin
IL Receptor
TGF-beta/Smad
Phosphatase
Aurora Kinase
Ras
JNK
PDE
HER
MAPK
P-gp
MEK
Tyrosine Kinases
DUB
IκB/IKK
NO Synthase
ROCK
Mitophagy
ROS
Lipoxygenase
SARS-CoV
p53
NMDAR
Virus Protease
Serine/threonin kinase
CXCR
HIF/HIF Prolyl-Hydroxylase
S1P Receptor
DNA-PK
PKA
RIP kinase
Hedgehog/Smoothened
HSV
IGF-1R
P2X Receptor
Neurokinin receptor
LPL Receptor
Nrf2
c-RET
E1/E2/E3 Enzyme
Drug Metabolite
TLR
NOD
S6 Kinase
FAK
Cholinesterase (ChE)
Antiviral
HIF
GluR
ATM/ATR
PLK
Sigma receptor
NOS
Mitochondrial Metabolism
Interleukin
TAM Receptor
Chloride channel
Proton pump
Serotonin Transporter
Norepinephrine
Casein Kinase
Tyrosinase
Proteasome
PERK
HBV
HCV Protease
RAAS
Gamma-secretase
Chk
Trk receptor
Phospholipase
Mdm2
Rho
Beta Amyloid
Protease-activated Receptor
DNA Alkylator/Crosslinker
Histone Demethylase
Pim
Endothelin Receptor
IRAK
Carbonic Anhydrase
Neuropeptide Y Receptor
PROTACs
Glucagon Receptor
SGLT
Retinoid Receptor
PDK
Syk
P2Y Receptor
MAO
Antifection
Guanylate cyclase
Smo
Bradykinin Receptor
Vasopressin Receptor
Melanocortin Receptor
DHFR
DYRK
Fatty Acid Synthase
cAMP
Histone Acetyltransferase
transporter
Reverse Transcriptase
c-Fms
Kras
Transferase
c-Myc
Cholecystokinin Receptor
LPA Receptor
Anti-infection
DNA Methyltransferase
CFTR
PD-1/PD-L1
Integrin
DNA Alkylation
OX Receptor
CaMK
DNA
GNRH Receptor
Leukotriene Receptor
IRE1
ROS Kinase
ADC Cytotoxin
NADPH
Progesterone Receptor
Antifolate
ABC Transporter
PI4K
Kinesin
Monoamine Oxidase
YAP
GTPase
Serine Protease
Neurotensin Receptor
IAP
Indoleamine 2,3-Dioxygenase (IDO)
HMG-CoA Reductase
NOD-like Receptor (NLR)
Somatostatin
GHSR
BTK
Monocarboxylate transporter
Reductase
MRP
Immunology/Inflammation related
CSF-1R
CCR
Aromatase
GRK
GPCR19
Ligand for E3 Ligase
Glutathione Peroxidase
Melatonin Receptor
Aryl Hydrocarbon Receptor
Bombesin Receptor
AhR
CaSR
FXR
Monoamine Transporter
Telomerase
BCRP
MNK
Free radical scavengers
Ephrin Receptor
Apelin receptor
LTR
Arrestin
BACE
IFNAR
Cysteine Protease
LIM Kinase
Myosin
Glucosidase
PAK
Wee1
PGE Synthase
Acyltransferase
STING
APC/C
Thrombin
MicroRNA
CRM1
Na+/Ca2+ Exchanger
Tie-2
OCT
Glucokinase
Glutaminase
UGT
LDL
Molecular Glues
Isocitrate Dehydrogenase (IDH)
PTEN
Oxytocin Receptor
Hydroxylase
MLK
Melanin-concentrating Hormone Receptor (MCHR)
Amino Acids and Derivatives
Ligands for Target Protein for PROTAC
NAMPT
PYK2
SIK
Annexin A
PAFR
MT Receptor
Lipid
Beta-Secretase
OAT
Survivin
CRFR
MELK
RSV
GST
GPX
ribosome
SGK
Cell Cycle Arrest
Liver X Receptor
MTH1
DPP-4
FAAH
ACK1
Xanthine Oxidase
Porcupine
ASK
Methionine Adenosyltransferase (MAT)
CRISPR/Cas9
CGRP Receptor
Discoidin Domain Receptor (DDR)
Platelet aggregation
BMI-1
NPC1L1
MALT
ROR
TOPK
Kisspeptin
VDAC
Hck
IDO
Adiponectin Receptor
DNA gyrase
Hexokinase
PAD
ATP Citrate Lyase
LRRK2
Aminopeptidase
Decarboxylase
TSH Receptor
PAI-1
Hippo pathway
Aquaporin
Adenosine Deaminase
p97
PKM
Adenylyl Cyclase
RAR/RXR
Factor Xa
Galectin
AAK1
RANKL/RANK
Haspin Kinase
Na-K-Cl cotransporter
HCN Channel
Epoxide Hydrolase
KSP
CD73
Pyroptosis
Carboxypeptidase
KLF
Complement System
NADPH-oxidase
Imidazoline Receptor
EBI2/GPR183
NEDD8
MyD88
Arginase
Cell wall
Lipase
gp120/CD4
VDA
Amylase
OXPHOS
PSMA
Glutathione reductase
AIM2
GluCls
HuR
Protease
RXFP receptor
Gap Junction Protein
DAPK
Lysosomal Autophagy
Vitamin
Thyroid hormone receptor(THR)
Advanced Glycation End Products
Transaminase
Hydrogenase
CD38
CYP19A1
Piezo Channel
NUDIX hydrolase
Dynamin
Neuropeptide W
Necroptosis
N-Acetylglucosaminyltransferase
Stemness kinase
FLAP
Phosphorylase
GlyT
Anion Exchanger
PROTAC Linker
Thioredoxin
Stearoyl-CoA Desaturase (SCD)
Angiotensin-converting Enzyme (ACE)
Transketolase
Thrombopoietin Receptor
cGAS
hCE
Neprilysin
Glyoxalase
Sodium-dependent phosphate transporter
IGF-2R
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