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Anti-GITR/TNFRSF18 Antibody (8R877)
还可以产品编号 TMAY-02614
Anti-GITR/TNFRSF18 Antibody (8R877) 是一种 Mouse 抗体，靶向 GITR/TNFRSF18。Anti-GITR/TNFRSF18 Antibody (8R877) 可用于 ELISA。
Anti-GITR/TNFRSF18 Antibody (8R877)
Anti-GITR/TNFRSF18 Antibody (8R877)
还可以产品编号 TMAY-02614
Anti-GITR/TNFRSF18 Antibody (8R877) 是一种 Mouse 抗体，靶向 GITR/TNFRSF18。Anti-GITR/TNFRSF18 Antibody (8R877) 可用于 ELISA。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-GITR/TNFRSF18 Antibody (8R877) is a Mouse antibody targeting GITR/TNFRSF18. Anti-GITR/TNFRSF18 Antibody (8R877) can be used in ELISA. |
| Ig Type | Monoclonal Mouse IgG2a |
| 克隆号 | 8R877 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human GITR/TNFRSF18/CD357 (rh GITR/TNFRSF18/CD357; TMPY-00072; NP_683700.1; Met1-Glu161). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases. It also mediates NF-kappa-B activation via the TRAF2/NIK pathway.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human GITR/TNFRSF18/CD357 Protein (TMPY-00072) |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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