Name: Anti-CD83 Antibody-PE (3W245)
Brand: TargetMol
SKU: TMAY-03408P
Rating: 4.5 (1 reviews)

Anti-CD83 Antibody-PE (3W245)

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产品编号 TMAY-03408P 别名 CD83 molecule

Anti-CD83 Antibody-PE (3W245) 是一种 PE-conjugated Rabbit 抗体，靶向 CD83。Anti-CD83 Antibody-PE (3W245) 可用于 FCM。

规格	价格	库存	数量
25 T	¥ 890	5日内发货
100 T	¥ 2,790	5日内发货

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常见问题解答

问化合物带有盐酸盐离子、硫酸盐离子等是否和其本身有什么区别？盐形式和游离态有什么区别？

答盐和非盐形式化合物的活性分子是一样的，在生物实验中起到的效果也一致，活性和使用方法都是一样的。只是由于呈盐不同，物理性质比如溶解度会有差异。建议您根据溶解、实验需求进行选择。

问如何选择某个靶点的特异性或总的抑制剂？特异性和非特异性的区别是什么？

答抑制剂按照特异性分为广谱 pan 和特异性 selective 两种。Pan 为某个靶点总的抑制剂，对所有亚型或整个家族的成员都有抑制作用。Selective 抑制剂针对某个蛋白激酶的某个亚型或家族中某个成员抑制率特别高或有特异性抑制作用。一般评价一个抑制剂的抑制效率主要看 IC50 值，IC50 值越低，说明抑制剂效率越高。建议您根据以上几个特征进行综合选择，也可联系技术帮您推荐相关抑制剂。

产品介绍

生物活性

产品描述	Anti-CD83 Antibody-PE (3W245) is a PE-conjugated Rabbit antibody targeting CD83. Anti-CD83 Antibody-PE (3W245) can be used in FCM.
别名	CD83 molecule
Ig Type	Rabbit IgG
克隆号	3W245
交叉反应	Mouse
验证活性	Flow cytometric analysis of Mouse CD83 expression on LPS-stimulated BABL/c splenocytes. Cells were stained with PE-conjugated anti-Mouse CD83. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
应用	FCM
推荐剂量	5 μl/Test, 0.1 mg/ml
抗体种类	Monoclonal
宿主来源	Rabbit
构建方式	This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD83 / HB15 (rM CD83 / HB15; TMPY-02156; O88324; Met1-Arg133) and conjugated with PE under optimum conditions, the unreacted PE was removed.
纯化方式	Protein A
性状	Liquid
缓冲液	PBS solution containing 0.5% BSA and 0.03%ProClin300
研究背景	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD83 is considered as a marker of mature dendritic cells as well as an adhesion receptor that binds to resting monocytes and a subset of activated CD8+T cells. In certain conditions, CD83 tended to dimerize or even multimerize through its aberrant intermolecular disulfide bonds. The injection of CD83-Ig can significantly enhance the rate of tumor growth and inhibit the T cell growth.