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Anti-Phospho-CPLA2 (Ser505) Polyclonal Antibody

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货号 TMAB-10536

Anti-Phospho-CPLA2 (Ser505) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-CPLA2 (Ser505)。Anti-Phospho-CPLA2 (Ser505) Polyclonal Antibody 可用于 WB。

Anti-Phospho-CPLA2 (Ser505) Polyclonal Antibody

Anti-Phospho-CPLA2 (Ser505) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-10536

Anti-Phospho-CPLA2 (Ser505) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-CPLA2 (Ser505)。Anti-Phospho-CPLA2 (Ser505) Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
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100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-CPLA2 (Ser505) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CPLA2 (Ser505). Anti-Phospho-CPLA2 (Ser505) Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Horse,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Cytoplasmic vesicle. Note=Translocates to membrane vesicles in a calcium-dependent fashion.
组织特异性Expressed in various tissues such as macrophages, platelets, neutrophils, fibroblasts and lung endothelium.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated synthesised phosphopeptide: human CPLA2 around the phosphorylation site of Ser505
抗原种属
Human
基因名称
PLA2G4A
基因ID
5321
蛋白名称
Cytosolic phospholipase A2
Uniprot ID
P47712
功能
Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response.
化学信息
分子量Theoretical: 82 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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