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Anti-CD200RLa Antibody-Biotin (5K764)
还可以产品编号 TMAY-01941B
Anti-CD200RLa Antibody-Biotin (5K764) 是一种 Biotin-conjugated Mouse 抗体，靶向 CD200RLa。Anti-CD200RLa Antibody-Biotin (5K764) 可用于 ELISA。
Anti-CD200RLa Antibody-Biotin (5K764)
Anti-CD200RLa Antibody-Biotin (5K764)
还可以产品编号 TMAY-01941B
Anti-CD200RLa Antibody-Biotin (5K764) 是一种 Biotin-conjugated Mouse 抗体，靶向 CD200RLa。Anti-CD200RLa Antibody-Biotin (5K764) 可用于 ELISA。
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产品介绍
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抗原信息
| 产品描述 | Anti-CD200RLa Antibody-Biotin (5K764) is a Biotin-conjugated Mouse antibody targeting CD200RLa. Anti-CD200RLa Antibody-Biotin (5K764) can be used in ELISA. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 5K764 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 0.1-1 μg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD200RLa / CD200R1L (rh CD200RLa / CD200R1L; TMPY-01591; AAT00538.1; Met1-Leu239) and then biotinylated. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography and then biotinylated. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Cell surface glycoprotein CD2 receptor 2, also known as Cell surface glycoprotein CD2 receptor 1-like, Cell surface glycoprotein OX2 receptor 2, CD2 receptor-like 2, CD2Rla, CD2R1L and CD2R2, is a single-pass type I membrane protein which belongs to theCD2R family. CD2R1L / CD2R2. It contains oneIg-like C2-type (immunoglobulin-like) domain and oneIg-like V-type (immunoglobulin-like) domain. CD2 is a transmembrane protein delivering immunoregulatory signals after engagement of CD2R. A family of CD2Rs exist ( CD2R1, CD2R2, CD2R3, CD2R4 ) with different tissue expression and functional activity. In the presence of anti-CD2R2 / CD2R3 monoclonal antibodies (mAbs), bone-marrow cells cultured in the presence of (interleukin [IL]-4+granulocyte-macrophage colony-stimulating factor) differentiate into dendritic cells (DCs), which induce CD4+CD25+ Treg. Interaction between the relatively ubiquitously expressed molecule CD2 and one of its receptors, CD2R1, resulted in direct suppression of alloreactivity, engagement of alternate receptors led instead to altered differentiation of dendritic cells (DCs) from marrow precursors, which could in turn foster development of Foxp3(+) regulatory T cells. Unlike anti-CD2R1, anti-CD2R2 both promotes development of DCs with capacity to induce Treg and directly augments thymocyte production of Treg. |
| 偶联 | Biotin |
| 其他可选修饰符 | Unconjugated |
| 可提供抗体种类 | 2 |
| 免疫原 | Recombinant Human CD200RLa / CD200R1L protein (TMPY-01591) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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