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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-epithelial Sodium Channel gamma Polyclonal Antibody

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货号 TMAB-05631

Anti-epithelial Sodium Channel gamma Polyclonal Antibody 是一种 Rabbit 抗体，靶向 epithelial Sodium Channel gamma。Anti-epithelial Sodium Channel gamma Polyclonal Antibody 可用于 WB。

Anti-epithelial Sodium Channel gamma Polyclonal Antibody

Anti-epithelial Sodium Channel gamma Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-05631

Anti-epithelial Sodium Channel gamma Polyclonal Antibody 是一种 Rabbit 抗体，靶向 epithelial Sodium Channel gamma。Anti-epithelial Sodium Channel gamma Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-epithelial Sodium Channel gamma Polyclonal Antibody is a Rabbit antibody targeting epithelial Sodium Channel gamma. Anti-epithelial Sodium Channel gamma Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Apical cell membrane; Multi-pass membrane protein. Note=Apical membrane of epithelial cells.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Epithelial sodium channels are amiloride-sensitive members of the Degenerin/epithelial sodium channel (Deg/ENaC) superfamily of ion channels. Members of this superfamily of ion channels share organizational similarity in that they all possess two short intracellular amino and carboxyl termini, two short membrane spanning segments, and a large extracellular loop with a conserved cysteine-rich region. There are three homologous isoforms of the ENaC (alpha, beta, and gamma) protein. ENaC in the kidney, lung, and colon plays an essential role in trans-epithelial sodium and fluid balance. ENaC also mediates aldosterone-dependent sodium reabsorption in the distal nephron of the kidney, thus regulating blood pressure. ENaC is thought to be regulated, in part, through association with the cystic fibrosis transmembrane conductance regulator (CFTR) chloride ion channel. Gain-of-function mutations in beta- or gamma-ENaC can cause severe arterial hypertension (Liddel’s syndrome) and loss-of-function mutations in alpha- or beta-ENaC causes pseudohypoaldosteronism (PHA-1).
抗原信息
免疫原
KLH conjugated synthetic peptide: human epithelial Sodium Channel gamma
抗原种属
Human
基因名称
SCNN1G
基因ID
6340
蛋白名称
Epithelial sodium channel subunit gamma
Uniprot ID
P51170
功能
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
化学信息
分子量Theoretical: 71 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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