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Anti-LILRA3/CD85e Antibody (2I935) 是一种 Rabbit 抗体,靶向 LILRA3/CD85e。Anti-LILRA3/CD85e Antibody (2I935) 可用于 FCM。
Anti-LILRA3/CD85e Antibody (2I935) 是一种 Rabbit 抗体,靶向 LILRA3/CD85e。Anti-LILRA3/CD85e Antibody (2I935) 可用于 FCM。
产品描述 | Anti-LILRA3/CD85e Antibody (2I935) is a Rabbit antibody targeting LILRA3/CD85e. Anti-LILRA3/CD85e Antibody (2I935) can be used in FCM. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 2I935 |
交叉反应 | Human |
验证活性 | Flow cytometric analysis of Human LILRA3(CD85e) expression on human whole blood monocytes. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with purified anti-Human LILRA3(CD85e), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes. |
应用 | FCM |
推荐剂量 | FCM: 1:25-1:100 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human LILRA3/CD85e/ILT6 (rh LILRA3/CD85e/ILT6; TMPY-03696; AAH28208.1; Met1-Glu439). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | ILT6, also known as LILRA3, belongs to the ILT family. In humans, the ILT gene family includes up to 11 members. The extracellular portion of all members includes at least two and usually four immunoglobulin domains. ILT-2 through 5 are all inhibitory members having variable numbers of cytoplasmic ITIM domains. ILT6 lacks a transmembrane domain. The function of ILT6 is currently unknown. however it is highly homologous to other LILR genes, and can bind human leukocyte antigen (HLA) class I. Therefore, if secreted, the ILT6 might impair interactions of membrane-bound LILRs (such as LILRB1, an inhibitory receptor expressed on effector and memory CD8 T cells) with their HLA ligands, thus modulating immune reactions and influencing susceptibility to disease. |
偶联 | Unconjugated |
其他可选修饰符 | FITC/PE |
可提供抗体种类 | 3 |
免疫原 | Recombinant Human LILRA3/CD85e/ILT6 Protein (TMPY-03696) |
抗原种属 | Human |
研究领域 | ITIM/ITAM Immunoreceptors and Related Molecules |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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