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Anti-LILRA3/CD85e Antibody (2I935)

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产品编号 TMAY-02601

Anti-LILRA3/CD85e Antibody (2I935) 是一种 Rabbit 抗体,靶向 LILRA3/CD85e。Anti-LILRA3/CD85e Antibody (2I935) 可用于 FCM。

Anti-LILRA3/CD85e Antibody (2I935)

Anti-LILRA3/CD85e Antibody (2I935)

Rating icon 还可以
产品编号 TMAY-02601

Anti-LILRA3/CD85e Antibody (2I935) 是一种 Rabbit 抗体,靶向 LILRA3/CD85e。Anti-LILRA3/CD85e Antibody (2I935) 可用于 FCM。

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产品介绍

生物活性
产品描述
Anti-LILRA3/CD85e Antibody (2I935) is a Rabbit antibody targeting LILRA3/CD85e. Anti-LILRA3/CD85e Antibody (2I935) can be used in FCM.
Ig Type
Monoclonal Rabbit IgG
克隆号
2I935
交叉反应
Human
验证活性
Flow cytometric analysis of Human LILRA3(CD85e) expression on human whole blood monocytes. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with purified anti-Human LILRA3(CD85e), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes.
应用
FCM
推荐剂量
FCM: 1:25-1:100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human LILRA3/CD85e/ILT6 (rh LILRA3/CD85e/ILT6; TMPY-03696; AAH28208.1; Met1-Glu439).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景ILT6, also known as LILRA3, belongs to the ILT family. In humans, the ILT gene family includes up to 11 members. The extracellular portion of all members includes at least two and usually four immunoglobulin domains. ILT-2 through 5 are all inhibitory members having variable numbers of cytoplasmic ITIM domains. ILT6 lacks a transmembrane domain. The function of ILT6 is currently unknown. however it is highly homologous to other LILR genes, and can bind human leukocyte antigen (HLA) class I. Therefore, if secreted, the ILT6 might impair interactions of membrane-bound LILRs (such as LILRB1, an inhibitory receptor expressed on effector and memory CD8 T cells) with their HLA ligands, thus modulating immune reactions and influencing susceptibility to disease.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
FITC/PE
可提供抗体种类
3
抗原信息
免疫原
Recombinant Human LILRA3/CD85e/ILT6 Protein (TMPY-03696)
抗原种属
Human
研究领域
ITIM/ITAM Immunoreceptors and Related Molecules
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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