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Anti-DIAPH1 Antibody (6T639)
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产品编号 TMAC-01148
别名 Protein diaphanous homolog 1, p140DIA, low frequency hearing loss 1, LFHL1, hDIA1, FLJ25265, DRF1, Diaphanous-related formin-1, Diaphanous related formin 1, Diaphanous homolog 1 (Drosophila), diaphanous homolog 1, DIAPH1, DIAPH 1, DIAP1_HUMAN, DIAP1, DIA1, DFNA1, deafness, autosomal dominant 1
Anti-DIAPH1 Antibody (6T639) 是一种 Rabbit 抗体，靶向 DIAPH1。Anti-DIAPH1 Antibody (6T639) 可用于 WB,ICC,IF,IHC。
Anti-DIAPH1 Antibody (6T639)
Anti-DIAPH1 Antibody (6T639)
还可以产品编号 TMAC-01148 别名 Protein diaphanous homolog 1, p140DIA, low frequency hearing loss 1, LFHL1, hDIA1, FLJ25265, DRF1, Diaphanous-related formin-1, Diaphanous related formin 1, Diaphanous homolog 1 (Drosophila), diaphanous homolog 1, DIAPH1, DIAPH 1, DIAP1_HUMAN, DIAP1, DIA1, DFNA1, deafness, autosomal dominant 1
Anti-DIAPH1 Antibody (6T639) 是一种 Rabbit 抗体，靶向 DIAPH1。Anti-DIAPH1 Antibody (6T639) 可用于 WB,ICC,IF,IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,480 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
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| 产品描述 | Anti-DIAPH1 Antibody (6T639) is a Rabbit antibody targeting DIAPH1. Anti-DIAPH1 Antibody (6T639) can be used in WB,ICC,IF,IHC. |
| 别名 | Protein diaphanous homolog 1, p140DIA, low frequency hearing loss 1, LFHL1, hDIA1, FLJ25265, DRF1, Diaphanous-related formin-1, Diaphanous related formin 1, Diaphanous homolog 1 (Drosophila), diaphanous homolog 1, DIAPH1, DIAPH 1, DIAP1_HUMAN, DIAP1, DIA1, DFNA1, deafness, autosomal dominant 1 |
| Ig Type | IgG |
| 交叉反应 | Human |
| 验证活性 | 1. Western blot analysis of DIAPH1 on SiHa cell lysate using anti-DIAPH1 antibody at 1/5,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-DIAPH1 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-DIAPH1 antibody. Counter stained with hematoxylin. 4. ICC staining DIAPH1 in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| 应用 | |
| 推荐剂量 | WB: 1:5000-10000; IHC: 1:50-100; ICC: 1:50 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Dia 1, also known as DIAPH1 (diaphanous homolog 1) or DRF1, a mammalian homolog of the Drosophila diaphanous gene, belongs to a family of formin homology (FH) proteins which are characterized by having tandemly aligned FH1 (formin homology 1) and FH2 (formin homology 2) domains in their carboxy terminal regions. Dia 1 contains a DAD (diaphanous autoregulatory) domain, which is involved in the elongation of actin filaments, and a GBD/FH3 (Rho GTPase-binding/formin homology 3) domain, which interacts with the DAD domain via autoinhibitory interactions to regulate the activation of Dia 1. Dia 1 is required for the assembly of F-actin structures, and regulates the polymerization and depolymerization of actin filaments. Localizing to the cell membrane, Dia 1 is expressed in a wide range of tissues, including brain, heart, lung and kidney. Defects to the gene encoding Dia 1 have been linked to deafness autosomal dominant type 1 (DFNA1), a disorder characterized by sensorineural hearing loss.. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: N-terminal human DIAPH1 |
| 抗原种属 | human |
| Uniprot ID |
| 分子量 | Theoretical: 141 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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