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顶部生物活性储存和溶解信息计算器

Anti-CTHRC1 Antibody (1O731)

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Anti-CTHRC1 Antibody (1O731)
产品编号 TMAY-01960
别名 collagen triple helix repeat containing 1

Anti-CTHRC1 Antibody (1O731) 是一种 Rabbit 抗体，靶向 CTHRC1。Anti-CTHRC1 Antibody (1O731) 可用于 ELISA(Cap)。

Anti-CTHRC1 Antibody (1O731)
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Anti-CTHRC1 Antibody (1O731)

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Anti-CTHRC1 Antibody (1O731)
产品编号 TMAY-01960 别名 collagen triple helix repeat containing 1

Anti-CTHRC1 Antibody (1O731) 是一种 Rabbit 抗体，靶向 CTHRC1。Anti-CTHRC1 Antibody (1O731) 可用于 ELISA(Cap)。

规格价格库存数量
20 μL
¥ 785
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100 μL
¥ 2,289
5日内发货
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产品介绍

生物活性
产品描述
Anti-CTHRC1 Antibody (1O731) is a Rabbit antibody targeting CTHRC1. Anti-CTHRC1 Antibody (1O731) can be used in ELISA(Cap).
别名collagen triple helix repeat containing 1
Ig Type
Rabbit IgG
克隆号
1O731
交叉反应
Human
应用
ELISA(Cap)
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human CTHRC1 (rh CTHRC1; TMPY-01395; NP_612464.1; Met1-Lys243).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Collagen triple helix repeat-containing protein 1, also known as Protein NMTC1, and CTHRC1, is a secreted protein that is glycosylated and highly conserved from lower chordates to mammals. CTHRC1 expression was not detectable in normal arteries. However, it is transiently expressed in the arterial wall in response to injury where it may contribute to vascular remodeling by limiting collagen matrix deposition and promoting cell migration. A short collagen motif with 12 Gly-X-Y repeats appears to be responsible for trimerization of the CTHRC1 protein and this renders the molecule susceptible to cleavage by collagenase. CTHRC1 overexpression caused a dramatic reduction in collagen type I mRNA and protein levels. Currently available data indicate that Cthrc1 expression in vascular cells regulates transforming growth factor beta responsiveness, thereby impacting transforming growth factor beta target genes, including collagens. Additionally, CTHRC1 increases bone mass as a positive regulator of osteoblastic bone formation and offers an anabolic approach for the treatment of osteoporosis.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human CTHRC1 Protein (TMPY-01395)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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