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顶部生物活性储存和溶解信息计算器

Anti-SIRP beta 1 Antibody (4S571)

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产品编号 TMAY-03477

别名 SIRP-β/Sirpb1a, SIRP-β, SIRP-beta, Sirpb1a, Sirpb1, Sirpb, 99327N5Rik

Anti-SIRP beta 1 Antibody (4S571) 是一种 Rabbit 抗体，靶向 SIRP beta 1。Anti-SIRP beta 1 Antibody (4S571) 可用于 ELISA。

Anti-SIRP beta 1 Antibody (4S571)

Anti-SIRP beta 1 Antibody (4S571)

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产品编号 TMAY-03477 别名 SIRP-β/Sirpb1a, SIRP-β, SIRP-beta, Sirpb1a, Sirpb1, Sirpb, 99327N5Rik

Anti-SIRP beta 1 Antibody (4S571) 是一种 Rabbit 抗体，靶向 SIRP beta 1。Anti-SIRP beta 1 Antibody (4S571) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,279
5日内发货
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产品介绍

生物活性
产品描述
Anti-SIRP beta 1 Antibody (4S571) is a Rabbit antibody targeting SIRP beta 1. Anti-SIRP beta 1 Antibody (4S571) can be used in ELISA.
别名SIRP-β/Sirpb1a, SIRP-β, SIRP-beta, Sirpb1a, Sirpb1, Sirpb, 99327N5Rik
Ig Type
Rabbit IgG
克隆号
4S571
交叉反应
Mouse
特异性
Mouse SIRP-beta/Sirpb1a
应用ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse SIRPB1A (rM SIRPB1A; TMPY-02388; BAD26610.1; Met1-Lys363).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景SIRPB1A (Signal-regulatory protein beta 1A), also known as SIRP beta 1, belongs to signal-regulatory-protein (SIRP) family, and immunoglobulin superfamily. Signal-regulatory proteins (SIRPs) are cell-surface glycoproteins expressed on myeloid and neural cells that have been shown to recruit SH2 domain-containing protein phosphatase 1 (SHP-1) and SHP-2 and to regulate receptor tyrosine kinase-coupled signaling. SIRP are classified as SIRP alpha molecules, containing 11- to 113-amino acid long, or SIRP beta molecules, with a 5-amino acid long intracytoplasmic domain. SIRP beta 1 is a new DAP12-associated receptor involved in the activation of myeloid cells, which contains a short cytoplasmic domain that lacks sequence motifs capable of recruiting SHP-1 and SHP-2. SIRP beta 1 acts as an activating isoform of SIRP alpha molecules, confirming the co-existence of inhibitory ITIM-bearing molecules, recruiting SHP-1 and SHP-2 protein tyrosine phosphatases, and activating counterparts, whose engagement couples to protein tyrosine kinases via ITAM-bearing molecules.s
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Mouse SIRPB1A protein (TMPY-02388)
抗原种属
Mouse
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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